30-0050
Talc
CP
Synonym(s):
Hydrous magnesium silicate
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About This Item
Linear Formula:
3MgO·4SiO2·H2O
CAS Number:
Molecular Weight:
379.27
UNSPSC Code:
12352300
PubChem Substance ID:
MDL number:
InChI
1S/3Mg.4O2Si.H2O.3O/c;;;4*1-3-2;;;;/h;;;;;;;1H2;;;
SMILES string
O.O=[Mg].O=[Mg].O=[Mg].O=[Si]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O
InChI key
FPAFDBFIGPHWGO-UHFFFAOYSA-N
grade
CP
form
solid
availability
available only in Japan
Storage Class
11 - Combustible Solids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Counterpoint: should thoracoscopic talc pleurodesis be the first choice management for malignant pleural effusion? No.
Richard W Light
Chest, 142(1), 17-19 (2012-07-17)
Todd L Demmy et al.
Journal of the National Comprehensive Cancer Network : JNCCN, 10(8), 975-982 (2012-08-11)
The optimal strategy to achieve palliation of malignant pleural effusions (MPEs) is unknown. This multi-institutional, prospective, randomized trial compares 2 established methods for controlling symptomatic unilateral MPEs. Patients with unilateral MPEs were randomized to either daily tunneled catheter drainage (TCD)
Thun How Ong et al.
Chest, 142(2), 511-513 (2012-08-09)
Pulmonary disease caused by talc is well described, but previous reports mainly describe lung parenchymal involvement. We describe what is, to our knowledge, the first case in which inhalation of cosmetic talc led to intense endobronchitis and airway stricture. A
Point: Should thoracoscopic talc pleurodesis be the first choice management for malignant effusion? Yes.
Pyng Lee
Chest, 142(1), 15-17 (2012-07-17)
Treatment options for malignant pleural effusions: patient preference does matter.
Nick A Maskell
JAMA, 307(22), 2432-2433 (2012-05-23)
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