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Merck
CN

28-4780

D-Sorbitol

SAJ first grade, ≥97.0%

Synonym(s):

D-Glucitol

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About This Item

Empirical Formula (Hill Notation):
C6H14O6
CAS Number:
Molecular Weight:
182.17
EC Number:
200-061-5
UNSPSC Code:
41116130
PubChem Substance ID:
Beilstein/REAXYS Number:
1721899
MDL number:
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InChI

1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4+,5-,6-/m1/s1

InChI key

FBPFZTCFMRRESA-JGWLITMVSA-N

SMILES string

OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CO

grade

SAJ first grade

vapor density

<1 (vs air)

vapor pressure

<0.1 mmHg ( 25 °C)

assay

≥97.0%

availability

available only in Japan

mp

98-100 °C (lit.)

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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Arlene E Dent et al.
PloS one, 3(10), e3557-e3557 (2008-10-30)
Antibodies that impair Plasmodium falciparum merozoite invasion and intraerythrocytic development are one of several mechanisms that mediate naturally acquired immunity to malaria. Attempts to correlate anti-malaria antibodies with risk of infection and morbidity have yielded inconsistent results. Growth inhibition assays
Reddy Ranjith K Sama et al.
Journal of cellular physiology, 228(11), 2222-2231 (2013-04-30)
FUsed in Sarcoma/Translocated in LipoSarcoma (FUS/TLS or FUS) has been linked to several biological processes involving DNA and RNA processing, and has been associated with multiple diseases, including myxoid liposarcoma and amyotrophic lateral sclerosis (ALS). ALS-associated mutations cause FUS to
G Molino et al.
The Journal of laboratory and clinical medicine, 131(5), 393-405 (1998-05-30)
D-Sorbitol (SOR) is safe, is easy to measure, and has an exceptionally high extraction ratio in the normal liver of 0.93+/-0.05 (mean+/-SD). Together with the general interest in hepatic hemodynamics, these facts motivated us to review the usefulness of this
Shahram Attarian et al.
Orphanet journal of rare diseases, 9, 199-199 (2014-12-19)
Charcot-Marie-Tooth type 1A disease (CMT1A) is a rare orphan inherited neuropathy caused by an autosomal dominant duplication of a gene encoding for the structural myelin protein PMP22, which induces abnormal Schwann cell differentiation and dysmyelination, eventually leading to axonal suffering
J M van Griensven et al.
Clinical pharmacology and therapeutics, 58(6), 631-640 (1995-12-01)
To examine the effect of diabetes mellitus on the pharmacokinetics of tolrestat and to investigate its effect on red blood cell sorbitol levels according to a new pharmacodynamic model for this class of drugs. Single and multiple doses of tolrestat

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