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Merck
CN

28-4050

Sodium salicylate

SAJ first grade, ≥99.5%

Synonym(s):

2-Hydroxybenzoic acid sodium salt, Salicylic acid sodium salt, Sodium 2-hydroxybenzoate

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About This Item

Linear Formula:
HOC6H4COONa
CAS Number:
54-21-7
Molecular Weight:
160.10
EC Number:
200-198-0
UNSPSC Code:
12352302
PubChem Substance ID:
329752901
Beilstein/REAXYS Number:
3732792
MDL number:
MFCD00002440
Assay:
≥99.5%
Grade:
SAJ first grade
Form:
crystalline

Key Documents

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InChI

1S/C7H6O3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H,(H,9,10);/q;+1/p-1

InChI key

ABBQHOQBGMUPJH-UHFFFAOYSA-M

SMILES string

[Na+].Oc1ccccc1C([O-])=O

grade

SAJ first grade

vapor pressure

<0.1 hPa ( 25 °C)

assay

≥99.5%

form

crystalline

availability

available only in Japan

pH

6.85 (26.3 °C)

mp

>300 °C (lit.)

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pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

208.9 °F - Pensky-Martens closed cup

flash_point_c

98.3 °C - Pensky-Martens closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
U1540
U8265
U3229
U1986
U2788

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Sarah L Baldridge et al.
American journal of veterinary research, 72(10), 1305-1317 (2011-10-04)
To determine the pharmacokinetic parameters of xylazine, ketamine, and butorphanol (XKB) administered IM and sodium salicylate (SAL) administered PO to calves and to compare drug effects on biomarkers of pain and distress following sham and actual castration and dehorning. 40
Yan-Yan Su et al.
PloS one, 7(10), e46969-e46969 (2012-10-17)
Sodium salicylate (NaSal), an aspirin metabolite, can cause tinnitus in animals and human subjects. To explore neural mechanisms underlying salicylate-induced tinnitus, we examined effects of NaSal on neural activities of the medial geniculate body (MGB), an auditory thalamic nucleus that
Qian Zhang et al.
Acta biomaterialia, 8(3), 1316-1322 (2011-12-14)
Poly(amidoamine) (PAMAM) dendrons were prepared from hollow fiber membranes (HFM) consisting of bromomethylated poly(2,6-dimethyl-1,4-phenylene oxide) (BPPO) in a stepwise manner. The prepared HFM were characterized by Fourier transform infrared spectroscopy, elemental analysis, and scanning electron microscopy. The drug loading efficiency
Jos J Eggermont
Hearing research, 295, 140-149 (2012-02-15)
Animal models of tinnitus require a behavioral correlate thereof. Various conditioned response methods and gap-startle reflex methods are in use and the outcomes generally correspond with putative electrophysiological substrates of tinnitus. However, for salicylate-induced tinnitus there is discordance between the
Guang-Di Chen et al.
Hearing research, 295, 100-113 (2012-12-04)
High doses of sodium salicylate (SS) have long been known to induce temporary hearing loss and tinnitus, effects attributed to cochlear dysfunction. However, our recent publications reviewed here show that SS can induce profound, permanent, and unexpected changes in the
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