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Safety Information

09-1500

Sigma-Aldrich

Ethylenediaminetetraacetic acid iron(III) sodium salt

SAJ special grade, ≥95.0%

Synonym(s):

EDTA iron(III) sodium salt, Edathamil, Komplexon™ II

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About This Item

Linear Formula:
C10H12N2NaFeO8
CAS Number:
15708-41-5
Molecular Weight:
367.05
EC Number:
239-802-2
MDL number:
MFCD00078215
UNSPSC Code:
12352116
PubChem Substance ID:
329748704

grade

SAJ special grade

Assay

≥95.0%

form

crystalline

availability

available only in Japan

mp

80 °C

solubility

water: 72 g/L at 25 °C

shipped in

ambient

SMILES string

[Na+].[Fe+3].[O-]C(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC([O-])=O

InChI

1S/C10H16N2O8.Fe.Na/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;/q;+3;+1/p-4

InChI key

MKWYFZFMAMBPQK-UHFFFAOYSA-J

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Application

Used to eliminate enzyme inhibition by traces of heavy metals, and to inhibit enzymes that require divalent cations as cofactors. Iron-EDTA enhances damage due to reactive oxygen species, such as depletion of reduced glutathione, formation of methemoglobin, and lipid peroxidation.

Legal Information

Komplexon is a trademark of CU Chemie Uetikon AG

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
U1140
U9755
U9547
U8444
U2325

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Vani Amalrajan et al.
Food and nutrition bulletin, 33(3), 177-179 (2012-11-20)
Foods fortified with sodium iron ethylenediaminetetraacetate (NaFeEDTA) have been shown to improve iron status in children, but little is known about the effect of this salt on urinary zinc excretion, particularly in children. This is particularly relevant, since zinc deficiency
Mehrdad Mohammadi et al.
Journal of the science of food and agriculture, 91(11), 1984-1989 (2011-04-16)
Sodium iron ethylenediaminetetraacetic acetate (NaFeEDTA) is a promising iron fortificant for populations consuming high-phytate diets. It produces fewer organoleptic effects than other fortificants do, especially when the matrix of the food vehicle contains fat, and has a bioavailability two to
Catherine W Macharia-Mutie et al.
The Journal of nutrition, 142(9), 1756-1763 (2012-07-20)
Few studies have evaluated the impact of fortification with iron-rich foods such as amaranth grain and multi-micronutrient powder (MNP) containing low doses of highly bioavailable iron to control iron deficiency anemia (IDA) in children. We assessed the efficacy of maize
Monica N Orozco et al.
Annals of nutrition & metabolism, 60(2), 108-114 (2012-03-15)
In any context of iron supplementation in the prenatal prophylaxis or therapeutic dosage range, a large amount will remain unabsorbed and pass through the intestinal tract into the colonic digesta possibly causing increased oxidation. To compare the generation of fecal
Barbara Troesch et al.
The Journal of nutrition, 141(5), 822-827 (2011-03-25)
The absorption profile of iron fortificants may be a determinant of their ability to generate nontransferrin-bound iron (NTBI) and, thus, their potential safety. Ferrous iron may be absorbed more rapidly than chelated ferric iron, but differences at the fortification level
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