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Merck
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CHROMTH-RO

Roche

Chromozym TH

Synonym(s):

thrombin substrate

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About This Item

UNSPSC Code:
12352204
NACRES:
NA.54
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assay

90% (Tosyl-Gly-Pro-Arg-4-nitranilide acetate (enzymatic))
90% (enzymatic)

form

powder

mol wt

Mr 662.62

packaging

pkg of 100 mg (11585398001)
pkg of 20 mg (10206849001)

manufacturer/tradename

Roche

shipped in

ambient

storage temp.

20-25°C

Quality Level

Analysis Note

Contaminant: 1% free 4-nitraniline

Application

Use Chromozym® TH as a substrate for the determination of serine proteases, specifically thrombin in aqueous solutions.

General description

Chromozym® TH is a chromophoric substrate mostly used to detect thrombin activity
Tosyl-Gly-Pro-Arg-4-nitranilide acetate

Other Notes

For life science research only. Not for use in diagnostic procedures.
Tosyl-glycyl-polyl-arginine-4-nitranilideacetate

Preparation Note

Working concentration: Approximately 0.2 mM
Storage conditions (working solution): 2 to 8 °C
A substrate solution (approx. 2 mM) is stable for at least 4 weeks if stored at 2 to 8 °C.

Legal Information

Chromozym is a registered trademark of Pentapharm AG, Basel

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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E Perzborn et al.
Journal of thrombosis and haemostasis : JTH, 3(3), 514-521 (2005-03-08)
BAY 59-7939 is an oral, direct Factor Xa (FXa) inhibitor in development for the prevention and treatment of arterial and venous thrombosis. BAY 59-7939 competitively inhibits human FXa (K(i) 0.4 nm) with > 10 000-fold greater selectivity than for other

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