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Merck
CN

11074440001

Roche

Penicillin-Streptomycin

suitable for cell culture, lyophilized (clear, colorless solution after reconstitution), non-sterile; 0.2 μm filtered, sufficient for 20 mL

Synonym(s):

antibiotic

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About This Item

UNSPSC Code:
12352207
NACRES:
NA.54
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sterility

non-sterile; 0.2 μm filtered

form

lyophilized (clear, colorless solution after reconstitution)

usage

sufficient for 20 mL

manufacturer/tradename

Roche

concentration

50 mg/mL streptomycin in 0.9% NaCl (as sulfate), 50,000 U/mL penicillin in 0.9% NaCl

technique(s)

cell culture | mammalian: suitable

antibiotic activity spectrum

Gram-negative bacteria, Gram-positive bacteria

mode of action

cell wall synthesis | interferes, protein synthesis | interferes

storage temp.

2-8°C

General description

Cytotoxic concentration: 10,000 IU/ml penicillin, 20 mg/ml streptomycin
Penicillin (Penicillin G) inhibits bacterial growth by inhibiting peptidoglycan synthesis. Streptomycin belongs to the family of aminoglycoside antibiotics, and inhibits bacterial growth by inhibiting protein synthesis. Penicillin-Streptomycin is used for the prevention and elimination of bacterial contaminants in cell culture.
Penicillin G, sodium salt; streptomycin sulfate
Sensitive organisms:
  • Gram-positive bacteria (penicillin)
  • Gram-negative bacteria (streptomycin)
  • Stability:Penicillin: 3 days
  • Streptomycin: 3 days in media at +37 °C

Application

Penicillin-Streptomycin has been used for the prevention and elimination of bacterial contaminants in cell culture.

Physical form

Lyophilizate, 50,000 U/ml penicillin G and 50 mg/ml streptomycin (as sulfate) in 0.9% NaCl

Preparation Note

Working concentration: 100 IU/ml penicillin
100 μg/ml streptomycin
Dissolve in 20mL distilled water.

Other Notes

For life science research only. Not for use in diagnostic procedures.


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pictograms

Exclamation markHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Repr. 2 - Resp. Sens. 1 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

Regulatory Information

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Selective BRAF inhibition decreases tumor-resident lymphocyte frequencies in a mouse model of human melanoma
Hooijkaas A, et al.
Oncoimmunology, 1(5), 609-617 (2012)
Disease relevant modifications of the methylome and transcriptome by particulate matter (PM2.5) from biomass combustion
He?elbach K, et al.
Epigenetics, 1-14 (2017)
Lysozyme and penicillin inhibit the growth of anaerobic ammonium-oxidizing planctomycetes.
Hu Z, et al.
Applied and Environmental Microbiology, 79(24), 7763-7769 (2013)



Global Trade Item Number

SKUGTIN
1107444000104061838698261