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Merck
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Y04D-02-5PK

CellASIC ONIX plate diploid yeast cells (4 chamber, 5-7 micron)

The Y04 plates for Diploid Yeast Cells utilize a microfabricated silicone ceiling with a height similar to yeast cells to restrict their growth in a single focal plane & maintaining x,y position over time.

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About This Item

UNSPSC Code:
41104923
NACRES:
NB.22
eCl@ss:
32011202
Material:
PMMA , glass , polycarbonate , polydimethylsiloxane (PDMS)
Manufacturer/tradename:
CellASIC® ONIX
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material

PMMA , glass , polycarbonate , polydimethylsiloxane (PDMS)

manufacturer/tradename

CellASIC® ONIX

W × L × H

85.48 mm × 127.76 mm × 14.35 mm

compatibility

for use with cells sized 5.0–7.0 μm

shipped in

ambient

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General description

Device Configuration: 4 chamber

Application

Research Category
Cell Culture

Legal Information

CELLASIC is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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The DNA damage checkpoint regulates a transition between yeast and hyphal growth in schizosaccharomyces japonicus.
Kanji Furuya, Hironori Niki
Molecular Cell Biology, vol. 30 no. 12, 2909-2917 (2010)

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Design dynamic experiments with the CellASIC™ ONIX Microfluidic Platform. With microfluidic precision, you can push the boundaries of your cell biology experiments in an in vivo-like environment. This new perfusion-based system enables you to program automated changes to culture conditions while maintaining optical access to cells through your microscope. You can even track individual cell responses over time by using a time-lapse-enabled microscope for truly dynamic cellular analysis.

We used the CellASIC™ ONIX MicroFluidic System, in conjunction with the M04S microfluidic plate, to achieve perfusion-based microenvironment control and study drug-induced cell death of 3D cultures of MCF7 cells in Matrigel®. The microfluidic chamber recreates the physiologic mass transport condition for optimized cell health. Four upstream fluidic channels allow controlled exposure of the cells to different solutions. The plate can also be cultured in a standard incubator using a dedicated gravity-driven flow channel. The cells are in contact with a #1.5 thickness (170 μm) optical glass surface, enabling high quality imaging using an inverted microscope. An integrated micro-incubator system delivers temperature and gas control to the microfluidic chambers.

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