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SCT046

Sigma-Aldrich

BioTracker CyP AP Live Cell Dye

Live cell imaging dye for alkaline phosphatase (AP) for cancer and stem cell applications.

Synonym(s):

Live cell imaging probe

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Select a Size

100 MG
CN¥529.62
500 MG
CN¥1,878.18
1 G
CN¥2,610.59
5 G
CN¥10,455.30

CN¥529.62

Available to ship onApril 23, 2025Details

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100 MG
CN¥529.62
500 MG
CN¥1,878.18
1 G
CN¥2,610.59
5 G
CN¥10,455.30

About This Item

UNSPSC Code:
12352207
NACRES:
NA.47

CN¥529.62

Available to ship onApril 23, 2025Details

Sign In for Best Price

Assay

≥98% (H-NMR)
≥98% (HPLC)
≥98% (LC/MS)
≥98% (elemental analysis)

technique(s)

cell based assay: suitable

detection method

fluorometric

shipped in

ambient

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53919U53918U53910U
Ascentis® Express RP-Amide, 2.7 μm HPLC Column 2.7 μm particle size, L × I.D. 15 cm × 2.1 mm

53914U

Ascentis® Express RP-Amide, 2.7 μm HPLC Column

Ascentis® Express RP-Amide, 2.7 μm HPLC Column 2.7 μm particle size, L × I.D. 15 cm × 3 mm

53919U

Ascentis® Express RP-Amide, 2.7 μm HPLC Column

Ascentis® Express RP-Amide, 2.7 μm HPLC Column 2.7 μm particle size, L × I.D. 10 cm × 3 mm

53918U

Ascentis® Express RP-Amide, 2.7 μm HPLC Column

Ascentis® Express RP-Amide, 2.7 μm HPLC Column 2.7 μm particle size, L × I.D. 3 cm × 2.1 mm

53910U

Ascentis® Express RP-Amide, 2.7 μm HPLC Column

particle size

2.7 μm

particle size

2.7 μm

particle size

2.7 μm

particle size

2.7 μm

matrix active group

amide, alkyl phase

matrix active group

amide, alkyl phase

matrix active group

amide, alkyl phase

matrix active group

amide, alkyl phase

matrix

Fused-Core® particle platform, superficially porous particle

matrix

Fused-Core® particle platform, superficially porous particle

matrix

Fused-Core® particle platform, superficially porous particle

matrix

Fused-Core® particle platform, superficially porous particle

technique(s)

HPLC: suitable, UHPLC-MS: suitable, LC/MS: suitable, UHPLC: suitable

technique(s)

HPLC: suitable, LC/MS: suitable, UHPLC-MS: suitable, UHPLC: suitable

technique(s)

HPLC: suitable, LC/MS: suitable, UHPLC-MS: suitable, UHPLC: suitable

technique(s)

HPLC: suitable, LC/MS: suitable, UHPLC-MS: suitable, UHPLC: suitable

pore size

90 Å

pore size

90 Å

pore size

90 Å

pore size

90 Å

General description

Alkaline Phosphatase (AP) catalyzes the hydrolysis of the phosphate group in alkaline media. AP is an essential enzyme and widely distributes in a variety of tissues such as liver, intestine, kidney, bone, and placenta. Abnormal AP levels have been shown in numerous cancers, bone disease and liver dysfunction. AP is also expressed by pluripotent stem cells such as ES and IPS cells.

The BioTracker CyP AP dye is a live cell near-infrared (NIR) fluorescent imaging probe for alkaline phosphatase. With its long emission wavelength, the probe is suitable for monitoring AP levels in both in vivo and in vitro tissues and cells. The probe possesses deep tissue penetration, less damage to the biological samples, and lower interference from the background fluorescence compared to other AP probes.

Spectral Properties
Absorbance: 690nm
Emission: 738nm

Application

Live cell fluorescent imaging
Research Category
Cell Imaging
Research Sub Category
Live Cell Dye

Quality

Purity: ≥ 98% confirmed by HNMR, LC-MS and HPLC and elemental analysis
Molar Mass: 528.55 g/mol

Physical form

Lyophilized

Storage and Stability

Store BioTracker CyP AP Live Cell Dye at -20°C, desiccate and protect from light
Note: Centrifuge vial briefly to collect contents at bottom of vial before opening.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

  • Specification Sheet

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    Song-Jiao Li et al.
    Analytical chemistry, 89(12), 6854-6860 (2017-05-19)
    Alkaline phosphatase (ALP) is an essential enzyme and widely distributes in a variety of tissues. To date, various nanomaterial and small-molecule fluorescent probes for ALP have been constructed successfully, but the emission wavelengths of these probes are in the ultraviolet

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