SCT023
BioTracker 664 NIR Ca2+ AM Dye
Live cell imaging calcium (Ca2+) indicator for neuroscience and cancer applications.
Synonym(s):
Live cell imaging probe
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About This Item
UNSPSC Code:
12161503
eCl@ss:
32161000
technique(s)
cell based assay: suitable
detection method
fluorometric
shipped in
ambient
General description
Calcium (Ca2+) play a vital role in the physiology and biochemistry of the cell. Calcium ions play an important role in signal transduction pathways, neurotransmitter release from neurons, contraction of all muscle cell types, and in fertilization. Extracellular calcium is also important for maintaining the potential difference across excitable cell membranes, as well as proper bone formation.
The BioTracker 664 NIR Ca2+ Dye is a live cell far-red fluorescent calcium indicator. The dye changes fluorescent intensity greatly (1000-fold) when it binds to calcium. Multicolor imaging is possible between the dye and Hoechst, Fluorescein, Rhodamine, GFP, YFP and RFP etc., which are fluorescent probes or fluorescent proteins having fluorescent wavelength from UV region to visible area. The advantages of long wavelength region are greater tissue penetration and low phototoxicity.
BioTracker 664 NIR Ca2+ Dye can be introduced by microinjection, patch clamp and electroporation. BioTracker 664 NIR Ca2+ AM Dye is an acetoxymethyl ester version and can permeate cell membranes.
Spectral Properties
Absorbance: 650nm
Emission: 664nm
The BioTracker 664 NIR Ca2+ Dye is a live cell far-red fluorescent calcium indicator. The dye changes fluorescent intensity greatly (1000-fold) when it binds to calcium. Multicolor imaging is possible between the dye and Hoechst, Fluorescein, Rhodamine, GFP, YFP and RFP etc., which are fluorescent probes or fluorescent proteins having fluorescent wavelength from UV region to visible area. The advantages of long wavelength region are greater tissue penetration and low phototoxicity.
BioTracker 664 NIR Ca2+ Dye can be introduced by microinjection, patch clamp and electroporation. BioTracker 664 NIR Ca2+ AM Dye is an acetoxymethyl ester version and can permeate cell membranes.
Spectral Properties
Absorbance: 650nm
Emission: 664nm
Application
Live cell fluorescent imaging
Research Category
Cell Imaging
Cell Imaging
Physical form
Lyophilized
Storage and Stability
Store BioTracker 664 NIR Ca2+ AM Dye at -20°C, desiccate and protect from light
Note: Centrifuge vial briefly to collect contents at bottom of vial before opening.
Note: Centrifuge vial briefly to collect contents at bottom of vial before opening.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Regulatory Information
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Certificates of Analysis (COA)
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