SCC225
YUMM 1.3 Mouse Melanoma Cell Line
Mouse
Synonym(s):
Yale University Mouse Melanoma 1.3 cell line, Yale University Mouse Melanoma cell line
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About This Item
UNSPSC Code:
41106514
NACRES:
NA.81
product name
YUMM 1.3 Mouse Melanoma Cell Line,
biological source
mouse
Quality Level
packaging
vial of ≥1X10⁶ vial
manufacturer/tradename
Millipore
technique(s)
cell culture | mammalian: suitable
shipped in
liquid nitrogen
storage temp.
−196°C
General description
YUMM1.3 cells are syngeneic with the immunocompetent C57BL/6 mouse background and retain genetic markers of the Braf/Pten mouse models, characterized by activation of Braf and inactivation of Pten and Cdkn2a.
Application
- Each vial contains >1X106 viable cells.
- YUMM1.3 cells are tested negative for infectious diseases by a Mouse Essential CLEAR panel by Charles River Animal Diagnostic Services.
- Cells are verified to be of mouse origin and negative for inter-species contamination from rat, chinese hamster, Golden Syrian hamster, human and non-human primate (NHP) as assessed by a Contamination CLEAR panel by Charles River Animal Diagnostic Services.
- Cells are negative for mycoplasma contamination.
Features and Benefits
The YUMM cell models recapitulate genetic drivers found in a significant proportion of human melanomas. YUMM1.3 cells retain genetic markers of the Braf/Pten mouse models, characterized by activation of Braf and inactivation of Pten and Cdkn2a, in which
Target description
Immunocompetent genetically-engineered mouse models harboring discrete genetic drivers of melanoma are essential for studying potential immunotherapies but are limited by the need to maintain colonies of multiple genotypes necessary to generate mouse mode
Storage and Stability
YUMM1.3 cells should be stored in liquid nitrogen until use. The cells can be cultured for at least 10 passages after initial thawing without significantly affecting the cell marker expression and functionality.
Other Notes
This product is intended for sale and sold solely to academic institutions for internal academic research use per the terms of the “Academic Use Agreement” as detailed in the product documentation. For information regarding any other use, please contact l
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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