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RADPKMAG-80K

MILLIPLEX® Rat Adipokine Panel

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About This Item

UNSPSC Code:
12161503
eCl@ss:
32161000
NACRES:
NA.84

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description

Configurable Rat Adipokine 7-Plex Panel

Quality Level

200

species reactivity

rat

manufacturer/tradename

Milliplex®

packaging

1 ea of

assay range

accuracy: 94-119%
sensitivity: 0.3-17 pg/mL
(MinDC)
standard curve range: 0.7-3,000 pg/mL
(IL-1β, TNFα)
standard curve range: 12-50,000 pg/mL
(PAI-1)
standard curve range: 15-60,000 pg/mL
(IL-6, Leptin)
standard curve range: 24-100,000 pg/mL
(Insulin)
standard curve range: 9.8-40,000 pg/mL
(MCP-1)

technique(s)

multiplexing: suitable

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

Related Categories

General description

Insulin, leptin, and PAI-1 regulate energy balance, glucose metabolism, and adipocyte function. IL-1β, IL-6, TNFα, and MCP-1/CCL2 are key inflammatory markers linked to metabolic dysfunction. Together, these biomarkers offer insight into immune-metabolic interactions in rat models of obesity and insulin resistance.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze 7 analytes in rat serum or plasma samples.

Analytes Included: IL-1β, IL-6, Insulin, Leptin, MCP-1/CCL2, PAI-1 (total), TNFα

Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.

Features and Benefits

Features:
  • Multiplex detection of 7 biomarkers in a single assay
  • Magnetic bead-based format for efficient and reproducible processing
  • Compatible with rat serum, plasma, and tissue lysates
  • High sensitivity for low-abundance targets
  • Short assay time (~4.5 hours) with minimal hands-on steps
Benefits:
  • Saves time and sample volume through multiplexing
  • Reduces assay variability and improves data quality
  • Enables comprehensive profiling of adipokine-related biomarkers
  • Supports research in obesity, diabetes, and metabolic syndrome
  • Facilitates translational studies in rat models of metabolic disease

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

Pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Sens. 1

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Regulatory Information

新产品
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Lin Song et al.
Biology of reproduction, 102(3), 705-716 (2019-11-20)
Maternal high-fat (HF) diet negatively affects maternal metabolism and placental function. This study aimed to determine whether gestational exercise prevents the effect of HF diet on placental amino acid transporter expression and nutrient-sensing signaling and the fetal response. Pregnant Sprague-Dawley
Jaroslava Trnovska et al.
International journal of molecular sciences, 22(19) (2021-10-14)
(1) Background: empagliflozin, sodium-glucose co-transporter 2 (SGLT-2) inhibitor, is an effective antidiabetic agent with strong cardio- and nephroprotective properties. The mechanisms behind its cardio- and nephroprotection are still not fully clarified. (2) Methods: we used male hereditary hypertriglyceridemic (hHTG) rats
Maria Monica Michicotl-Meneses et al.
Nutrients, 13(8) (2021-08-28)
Pomegranate juice (Punica granatum) has been used since ancient times in traditional medicine (Unani Medicine, Ayurveda); its main compounds are anthocyanins and ellagic acid, which have anti-inflammatory, antioxidant, hepatoprotective, and cardiovascular health effects. The objective was to evaluate the effect
Zongbin Song et al.
Scientific reports, 7(1), 10350-10350 (2017-09-06)
Obesity is associated with increased risk for chronic pain. Basic mechanisms for this association are poorly understood. Using a milder version of a radicular pain model, local inflammation of the dorsal root ganglion (DRG), we observed marked increases in mechanical

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96 well Template Single
Protocol- RADPKMAG-80K
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