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RADPCMAG-82K

MILLIPLEX® Rat Adipocyte Panel

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About This Item

UNSPSC Code:
12161503
NACRES:
NA.84
eCl@ss:
32161000

Key Documents

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Quality Level

200

description

Configurable Rat Adipocyte 7-Plex Panel

species reactivity

rat

manufacturer/tradename

Milliplex®

packaging

1 ea of

assay range

accuracy: 94-121%
sensitivity: 0.1-25 pg/mL
(MinDC+2SD)
standard curve range: 0.7-3,000 pg/mL
(IL-1β, TNFα)
standard curve range: 12-50,000 pg/mL
(PAI-1)
standard curve range: 122-500,000 pg/mL
(Adiponectin)
standard curve range: 15-60,000 pg/mL
(IL-6, Leptin)
standard curve range: 9.8-40,000 pg/mL
(MCP-1)

technique(s)

multiplexing: suitable

input

cell culture supernatant(s)

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

Biochem/physiol Actions

There was no or negligible cross-reactivity between the antibodies for an analyte and any of the other analytes within a panel.

General description

The MILLIPLEX® MAP Rat Adipocyte Magnetic Bead Panel is a 7-plex kit to be used for the simultaneous quantification of any or all of the following analytes in tissue/cell lysates and culture supernatant samples: Adiponectin, IL-1β, IL-6, Leptin, MCP-1, PAI-1 Total, and TNFα.
Adiponectin, leptin, and PAI-1 are key regulators of metabolism and insulin sensitivity, while IL-1β, IL-6, TNFα, and MCP-1/CCL2 are central to adipose tissue inflammation. Together, these biomarkers provide insight into metabolic dysfunction and immune-adipocyte interactions in rat models of obesity and related disorders.

Other Notes

Sensitivity: Please see kit protocol for individual assay sensitivities.

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 7 analytes in rat cell culture supernatants.

Analytes Included: Adiponectin, IL-1β, IL-6, Leptin, MCP-1/CCL2, PAI-1 (total), TNFα

Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

Features and Benefits

Features:

  • Multiplex detection of 7 adipokines and cytokines in a single assay
  • Magnetic bead-based format for efficient and reproducible processing
  • Compatible with rat serum, plasma, and tissue lysates
  • High sensitivity for low-abundance biomarkers
  • Utilizes Luminex® xMAP technology for high-throughput analysis
  • Short assay time (~4.5 hours) with minimal hands-on steps
Benefits:

  • Saves time and sample volume through multiplexing
  • Reduces assay variability and improves data quality
  • Enables comprehensive profiling of adipocyte-related biomarkers
  • Supports research in obesity, diabetes, and metabolic syndrome
  • Facilitates translational studies in rat models of metabolic disease

pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Sens. 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

Regulatory Information

新产品
This item has

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Monika Kubacka et al.
Pharmaceuticals (Basel, Switzerland), 14(5) (2021-06-03)
Quinazoline α1-adrenoceptors antagonists have been shown to exert moderately favorable effects on the metabolic profile in hypertensive patients. However, based on AntiHypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) results, they are no longer recommended as a first
Salvador Peiró Moreno et al.
Nutricion hospitalaria, 37(6), 1246-1280 (2020-10-16)
Background: the legislation currently regulating the inclusion of Food for Special Medical Purposes (FSMP) among the benefits of the National Health System (SNS) was made approximately 15 years ago. The evolution of the technical characteristics of the FSMP justifies an
Irene Bretón Lesmes et al.
Nutricion hospitalaria, 38(Spec No1), 8-14 (2021-02-03)
Nutritional assessment and treatment, necessary for the prevention and treatment of disease-related malnutrition, should be carried out by a multidisciplinary team where each member has well-defined skills and functions, and mechanisms are established to allow adequate coordination, both in the
Hamidah Abu Bakar et al.
Cardiovascular research, 113(8), 962-972 (2017-04-04)
Electrical field stimulation (EFS) elicits robust sensory neurogenic relaxation responses in the rat isolated mesenteric arterial bed but these responses are absent or difficult to demonstrate in isolated arteries. We believe that this mismatch is due to the absence of

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Quality Control Range Sheet- RAMAG-107 and RAMAG-207
Protocol- RADPCMAG-82K
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