PYR0MATKIT
PyroMAT® kit
Reagents and Interleukin-6 ELISA kit for Monocyte Activation Test (MAT), for Pyrogen testing
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UNSPSC Code:
41116129
eCl@ss:
32160606
NACRES:
NA.74
Recommended Products
Agency
EP Chapter 2.6.30
Quality Level
feature
ready-to-use
packaging
pkg of 1 kit
manufacturer/tradename
PyroMAT®
application(s)
pharmaceutical
pyrogen testing
compatibility
configured for PyroMAT®
shipped in
ambient
storage temp.
2-8°C
suitability
pyrogenic bacteria
Related Categories
General description
The PYROMAT® System is a ready-to-use, in vitro solution for pyrogen testing, using the Monocyte Activation Test (MAT). It is based on the Mono-Mac-6 cell line and interleukin 6 (IL-6) read-out. The human monocytes that encounter pyrogens from contaminated sample, produce cytokines (IL-6), which can be detected with an enzyme-linked immunosorbent assay (ELISA). The kit contains the reagents needed to prepare the sample, perform the incubation with the monocytic cells, and the reagents needed for the ELISA detection.
Application
The PYROMAT® System is used to ensure the safety of parenteral pharmaceutical products and medical devices.
Features and Benefits
Ready-to-use kit
Components
- 96-well plate, Endotoxin free water, RMPI culture medium
- IL-6 ELISA kit and plate
Storage and Stability
2-8°C
Recommended products
To be used with PYROMAT® cells (PYR0MATCELLS), Reference standard endotoxin (144.161.0001), NEP controls (MATHKSA, MATFLAGELLIN) and IL6 control (PYR0MATIL6)
Legal Information
PYROMAT is a registered trademark of Merck KGaA, Darmstadt, Germany
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Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Aquatic Chronic 2 - Eye Irrit. 2 - Met. Corr. 1 - Repr. 1B - Skin Irrit. 2 - Skin Sens. 1
WGK
WGK 3
Certificates of Analysis (COA)
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