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Safety Information

PCC030C15C

Millipore

Pellicon® Capsule with Ultracel® Membrane

pore size 30 kDa, C Screen, 1.5 m2 with AseptiQuik® G connectors

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UNSPSC Code:
41104903

material

EPDM rubber seal
PPO/PS blend (core)
PPO/PS blend housing
TPE seal
cellulose screen (Composite Regenerated)
composite regenerated cellulose (CRC) membrane
epoxy adhesive
polyester screen
polypropylene screen
polyurethane adhesive

Quality Level

sterility

sterile; γ-irradiated

product line

Pellicon®

storage condition

room temperature (15-30°C)

parameter

max. inlet pressure at 75 psi (5.1 bar) and 4-30 °C
max. transmembrane pressure at 50 psi (3.5 bar) and 4-30 °C
4-8 L/min-m2 flow rate

technique(s)

ultrafiltration: suitable

L

43.7 cm (17.2 in.)

diam.

10.3 cm (4.1 in.)

filtration area

1.5 m2

screen size

, Type C screen (coarse screen)

volume

455 mL , in feed channel
719 mL , in permeate channel

impurities

≤5 ppm Meets TOC (in retentate effluent, after a WFI flush of 20 L/m2)

matrix

Ultracel®

pore size

30 kDa

pH range

2-13

fitting

inlet/outlet connection (Feed: AseptiQuik® G Connector)
inlet/outlet connection (Permeate: AseptiQuik® G Connector)
inlet/outlet connection (Retentate: AseptiQuik® G Connector)

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General description

The Pellicon® Capsule is the first of its kind -- a true single-use TFF device that comes ready to process in minutes. Self-contained, it employs an easy-to-use, holderless format and is supplied sterilized by irradiation.

Application

Concentration, Diafiltration, Buffer exchange, Protein purification

Features and Benefits

Plug ′n play, holderless design - easy to install, safe to remove
Gamma sterilized and preseravtive-free - ready to process in minutes
True single-use, self-contained capusle - fast, safe, and flexible batch turnaround
Proven Ultracel® membrane and C screen - high recovery, superior mass transfer, solvent resistance
Pellicon® TFF proven performance - true linear scalability within Pellicon® TFF families

Packaging

A foam pouch is inserted over the end caps on both ends of the capsule which is then double-bagged and vacuum sealed. The double-bagged capsule is then placed on a tray and individually boxed.

Compatibility

Screen Type: Type C screen (coarse screen)

Other Notes

The Emprove® Program complements the product portfolio through

Comprehensive documentation to support qualification, risk assessment and process optimization needs.
Consolidation of product specific testing, quality and regulatory information to simplify compliance requirements.
Convenient 24/7 access to up-to-date product information.

Legal Information

AseptiQuik is a registered trademark of Colder Products Company
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
Pellicon is a registered trademark of Merck KGaA, Darmstadt, Germany
ULTRACEL is a registered trademark of Merck KGaA, Darmstadt, Germany

Regulatory Information

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Articles

Find best practices for using Pellicon® Capsules in ADC processing as well as data from two studies using Pellicon® Capsules and Pellicon® cassettes in the ADC manufacturing process.

How are ultrafiltration and diafiltration used in plasmid DNA manufacturing and how should you optimize this process? Learn more in our technical article and download our free eBook.

Get practical guidance on using single-pass tangential flow filtration in your downstream process and scaling between capsules and cassettes.

Free eBook outlines plasmid DNA manufacturing process and downstream purification challenges for various applications.

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