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P2C005C05

Millipore

Pellicon® 2 Cassette Ultrafiltration Module

filtration area 0.5 m2, NMWCO 5 kDa

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Synonym(s):
Pellicon 2 Cassette Ultrafiltration Module PLCCC C 0.5m2
UNSPSC Code:
23151806

material

composite regenerated cellulose (CRC)
polypropylene screen
polyurethane adhesive

Quality Level

400

manufacturer/tradename

Pellicon®

parameter

0.33 bar max. transmembrane pressure (5 psig) (reverse)
3.5 bar max. transmembrane pressure (50 psig) at 30 °C (forward)
5-35 L/min recirculation rate at 0.4 bar (6 psi)

technique(s)

analytical sample preparation: suitable
protein purification: suitable

H

1.5 cm (0.6 in.)

L

21 cm (8.3 in.)

W

17.8 cm (7.0 in.)

filtration area

0.5 m2

membrane nominal area

0.5 m2

gravimetric extractables

≤1500 mg/m2

matrix

Ultracel®

pore size

5 kDa NMWCO

pH

2-13

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General description

The Pellicon® 2 Ultrafiltration PLCCC Cassette sets the standard in cassette-style tangential flow filtration devices. P2C005C05 was designed with process scale-up and applications development in mind.

Millipore′s PLCCC polyethersulfone membrane has void-free structures that guard against leakage of solutes through microdefects normally associated with voids beneath the thin skins of conventional UF membranes. These void-free membranes are more permeable, resulting in high-flux with equivalent or superior product retention. These void-free membranes provide the advantages of fast, high yield processing and smaller systems.

The Pellicon® 2 Cassette Ultrafiltration Module feature a filtration area of 0.5 m2 with a pore size of 5 kDa NMWCO.

Application

Concentration, desalting or buffer exchange of:
  • Protein solutions
  • Polysaccharide solutions
  • Virus suspensions


Harvest, washing or clarification of:
  • Cell cultures and lysates
  • Colloidal suspensions
  • Viral cultures

Features and Benefits

  • Type C screen (coarse screen)
  • Leading-edge void- free membranes to match virtually any separation challenge
  • Short flow path for higher flux and higher resolution separation capability
  • Choice of flow channel configuration providing process optimization capability
  • Predictable, fast, scale-up
  • True linear scalability from laboratory size modules to industrial assemblies for processing thousands of liters
  • Brings higher resolution, improved yields and superior back-pressure resistance
  • Ultracel membranes are composite membranes cast on a microporous substrate for defect-free membranes with superior

Other Notes

These products are manufactured in a facility which adheres to FDA Good Manufacturing Practices.
Prefiltration Rquirements: 100 µm

Analysis Note

Gravimetric Extractables: after a water flush

Legal Information

Pellicon is a registered trademark of Merck KGaA, Darmstadt, Germany
ULTRACEL is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 2

Regulatory Information

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