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MCVD1MAG-77K

Millipore

MILLIPLEX® Mouse Cardiovascular Disease (CVD) Magnetic Bead Panel 1 - Cardiovascular Disease Multiplex Assay

This MILLIPLEX MAP Mouse Cardiovascular Disease Magnetic Bead Panel 1 includes the following analytes: sE-Selectin, sICAM-1, Pecam-1, sP-Selectin, PAI-1 (total), proMMP-9 & Thrombomodulin.

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About This Item

UNSPSC Code:
12161503
eCl@ss:
32161000
NACRES:
NA.84

Quality Level

200

species reactivity

mouse

manufacturer/tradename

Milliplex®

assay range

accuracy: 88-99%
sensitivity: 0.008 ng/mL
(proMMP-9)
sensitivity: 0.012 ng/mL
(PAI-1 (total))
sensitivity: 0.012 ng/mL
(Pecam-1)
sensitivity: 0.013 ng/mL
(sICAM-1)
sensitivity: 0.033 ng/mL
(sE-Selectin)
sensitivity: 0.039 ng/mL
(Thrombomodulin)
sensitivity: 0.429 ng/mL
(sP-Selectin)
standard curve range: 0.007-30 ng/mL
(sICAM-1)
standard curve range: 0.012-50 ng/mL
(proMMP-9)
standard curve range: 0.018-75 ng/mL
(PAI-1 (total))
standard curve range: 0.024-100 ng/mL
(Pecam-1)
standard curve range: 0.024-100 ng/mL
(Thrombomodulin)
standard curve range: 0.049-200 ng/mL
(sE-Selectin)
standard curve range: 0.439-1800 ng/mL
(sP-Selectin)
inter-assay cv: <15%
intra-assay cv: <10%

technique(s)

multiplexing: suitable

detection method

fluorometric (Luminex xMAP)

shipped in

wet ice

Related Categories

General description

Cardiovascular disease, particularly atherosclerotic vascular disease, is a leading cause of global mortality, accounting for 30% of all global deaths (WHO, 2010). Inflammatory mechanisms play a vital role in the initiation, maintenance, and progression of vascular disease with a strong correlation between inflammatory markers and prognosis in acute and chronic coronary artery disease. Numerous studies have demonstrated an association of obesity and diabetes with cardiovascular risk factors.

MILLIPLEX® Mouse CVD Panel 1 is a 7-plex kit to be used for the simultaneous quantification of any or all of the following analytes in serum and plasma samples: sE-Selectin, sICAM-1, Pecam-1, sP-Selectin, PAI-1 Total, proMMP-9, and Thrombomodulin. This kit uses a 96-well format, contains a lyophilized standard cocktail, two internal assay quality controls and can measure up to 38 samples in duplicate.

The Luminex® xMAP® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.

Panel Type: Cardiovascular

Specificity

Cross Reactivty
Non-detectable within the panel

Application

  • Analytes: CD31 (sPecam-1), sE-Selectin, sICAM-1, PAI-1 (Total), ProMMP-9, sP-Selectin,
  • Thrombomodulin, s Recommended Sample Type: Mouse serum, plasma or cell/tissue culture supernatants or lysates
  • Recommended Sample Dilution: 25 μL per well of 1:20 diluted serum or plasma; cell/tissue culture samples may require dilution in appropriate control mediumAssay Run Time: Overnight (16-18 hours) at 2-8°C
  • Research Category: Cardiovascular Disease
  • Research Subcategory: Metabolism

Features and Benefits

Design your multiplex kit by choosing available analytes within this panel.

Other Notes

Please contact Technical Service for linearity of dilution.

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Sens. 1

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Regulatory Information

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Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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