MABN668
Anti-Ly6C Antibody, clone 6C3
clone 6C3, from rat
Synonym(s):
Lymphocyte antigen 6C2, Ly-6C2
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
biological source
rat
Quality Level
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
6C3, monoclonal
species reactivity
mouse
technique(s)
dot blot: suitable
flow cytometry: suitable
isotype
IgG2aκ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
mouse ... Ly6C1(17067)
Related Categories
General description
Lymphocyte antigen 6C2 (Ly6C) is a 131 AA long membrane protein that is linked to macrophage phenotype according to expression levels.
Immunogen
Whole cells expressing mouse Ly6C.
Application
Detect Lymphocyte antigen 6C2 using this rat monoclonal antibody, Anti-Ly6C Antibody, clone 6C3 validated for use in Flow Cytometry & Dot Blot.
Dot Blot Analysis: A representative lot from an independent laboratory detected Ly6C in bone marrow-derived monocytes expressing 6C3 (Butovsky, O., et al. (2012). J Clin Invest. 122(9):3063-3087.).
Research Category
Neuroscience
Neuroscience
Research Sub Category
Signaling Neuroscience
Signaling Neuroscience
Quality
Evaluated by Flow Cytometry in mouse spleen cells.
Flow Cytometry Analysis: 1 µg of this antibody detected Ly6C in 1X10E6 mouse spleen cells.
Flow Cytometry Analysis: 1 µg of this antibody detected Ly6C in 1X10E6 mouse spleen cells.
Target description
14 kDa calculated
Physical form
Format: Purified
Protein G Purified
Purified rat monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Storage and Stability
Stable for 1 year at 2-8°C from date of receipt.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Zhilong Jiang et al.
Respiratory research, 18(1), 217-217 (2017-12-30)
SOCS3 (suppressor of cytokine signaling 3) is a negative regulator of JAK/STAT3 signaling pathway and participates in the regulation of lung inflammation in a mouse model with acute lung injury (ALI). However, it is not well understood how SOCS3 regulates
Oleg Butovsky et al.
Nature neuroscience, 17(1), 131-143 (2013-12-10)
Microglia are myeloid cells of the CNS that participate both in normal CNS function and in disease. We investigated the molecular signature of microglia and identified 239 genes and 8 microRNAs that were uniquely or highly expressed in microglia versus
Qin Huang et al.
PloS one, 14(11), e0225206-e0225206 (2019-11-15)
The engineered AAV-PHP.B family of adeno-associated virus efficiently delivers genes throughout the mouse central nervous system. To guide their application across disease models, and to inspire the development of translational gene therapy vectors for targeting neurological diseases in humans, we
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