MABN502
Anti-SNAT1 Antibody, clone N104/37
clone N104/37, from mouse
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Sodium-coupled neutral amino acid transporter 1, Amino acid transporter A1, rATA1, Glutamine transporter, N-system amino acid transporter 2, Solute carrier family 38 member 1, System A amino acid transporter 1, System A transporter 2, System N amino acid
Recommended Products
biological source
mouse
antibody form
purified antibody
antibody product type
primary antibodies
clone
N104/37, monoclonal
species reactivity
mouse, human, rat
technique(s)
immunohistochemistry: suitable
western blot: suitable
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... SLC38A1(81539)
General description
Sodium-coupled neutral amino acid transporter 1 (SNAT) is also called, Amino acid transporter A1 (ATA1), Glutamine transporter (Glnt), N-system amino acid transporter 2, Solute carrier family 38 member 1 (SLC38A1), System A amino acid transporter 1 (SAT1), System A transporter 2 (SA2), and System N amino acid transporter 1. SNAT functions as a sodium-dependent amino acid transporter that may supply glutamatergic and GABAergic neurons with the glutamine required for the synthesis of the neurotransmitters glutamate and GABA. SNAT is specifically expressed in brain, with the highest levels in cerebellum and thalamus, in glutamatergic, GABAergic and dopaminergic neurons, ependymal cells lining the ventricle and is also detected in spinal cord, heart, colon and placenta.
Specificity
This antibody recognizes the N-terminus of SNAT1.
Immunogen
Epitope: N-terminus
Recombinant protein corresponding to the N-terminus of rat SNAT1.
Application
Detect Sodium-coupled neutral amino acid transporter 1 using this mouse monoclonal antibody, Anti-SNAT1 Antibody, clone N104/37 validated for use in western blotting & IHC.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected SNAT1 in rat midbrain and human thalamus tissue.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Developmental Signaling
Developmental Signaling
Quality
Evaluated by Western Blotting in human brain tissue lysate.
Western Blotting Analysis: 1.0 µg/mL of this antibody detected SNAT1 in 10 µg of human brain tissue lysate.
Western Blotting Analysis: 1.0 µg/mL of this antibody detected SNAT1 in 10 µg of human brain tissue lysate.
Target description
~ 54 kDa observed
Physical form
Format: Purified
Protein G Purified
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Storage and Stability
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Control
Human brain tissue lysate
Human brain tissue lysate
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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