Skip to Content
Merck
CN

MABN2529

Anti-Huntingtin Disease (HD/HTT) Antibody

mouse monoclonal, MW8

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Species reactivity:
mouse, human
Technique(s):
ELISA: suitable, immunocytochemistry: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable
Application:
ELISA, ICC, IHC, IP, WB
Citations:
-

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Anti-HTT Antibody, clone MW8,

species reactivity

mouse, human

technique(s)

ELISA: suitable, immunocytochemistry: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable

isotype

IgG2aκ

UniProt accession no.

P42858

antibody form

purified antibody

clone

MW8, monoclonal

purified by

using protein G

concentration

(Please refer to lot specific datasheet.)

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

347.6 kDa calclulated
HD exon-1 67Q aggregate.

Application

Immunocytochemistry Analysis: A representative lot detected HTT in Immunocytochemistry applications (Legleiter, J., et. al. (2009). J Biol Chem. 284(32):21647-58).

Immunohistochemistry Analysis: A representative lot detected HTT in Immunohistochemistry applications (Ko, J., et. al. (2001). Brain Res Bull. 56(3-4):319-29).

Western Blotting Analysis: A representative lot detected HTT in Western Blotting applications (Legleiter, J., et. al. (2009). J Biol Chem. 284(32):21647-58).

Enzyme Immunoassay (ELISA) Analysis: A representative lot detected HTT in ELISA applications (Ko, J., et. al. (2001). Brain Res Bull. 56(3-4):319-29).

Immunoprecipitation Analysis: A representative lot immunoprecipitated HTT in Immunoprecipitation applications (Baldo, B., et. al. (2012). Chem Biol. 19(2):264-75).

Western Blotting Analysis: A 1:1,000 dilution from a representative lot detected HTT in Tissue lysate of 9 month-old WT or Q140 KI HD mice.

Biochem/physiol Actions

Clone MW8 is a mouse monoclonal antibody that detects Huntingtin protein. It targets an epitope within nine amino acids in the exon-1 region.

Physical form

Purified mouse monoclonal antibody IgG2a in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Isotype testing: Identity Confirmation by Isotyping Test.

Isotyping Analysis: The identity of this monoclonal antibody is confirmed by isotyping test to be mouse IgG2a.

Other Notes

Human, Mouse.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service