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MABF311

Sigma-Aldrich

Anti-CD19 (mouse), PE, clone 6D5 Antibody

clone 6D5, from rat, PE

Synonym(s):

B-lymphocyte antigen CD19, Differentiation antigen CD19, CD19

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rat

conjugate

PE

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

6D5, monoclonal

species reactivity

mouse

technique(s)

flow cytometry: suitable

isotype

IgG2aκ

UniProt accession no.

P25918

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

mouse ... Cd19(12478)

General description

B-lymphocyte antigen CD19 (CD19), also known as Differentiation antigen CD19, is a transmembrane glycoprotein with two extracellular C2-type domains and is a critical signal transduction molecule that regulates B lymphocyte development, activation, and differentiation. CD19 expression is restricted to B cells, being absent from T cells, monocytes, and granulocytes. The CD19 antigen appears early during B cell maturation, probably at late pro-B cell stage around the time of Ig heavy chain rearrangement. It then persists during all stages of B cell maturation and is lost upon terminal differentiation to plasma cells.

Immunogen

Mouse CD19-expressing K562 human erythroleukemia cells.

Application

Anti-CD19 antibody (mouse), PE, clone 6D5 is a highly specific rat monoclonal antibody & that targets CD19 & has been tested in Flow Cytometry.
Research Category
Inflammation & Immunology
Research Sub Category
Cytokines & Cytokine Receptors

Quality

The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Flow Cytometry Analysis: 0.25 μg of this antibody detected in one million C57BL/6 mouse splenocytes.

Target description

60 kDa calculated

Physical form

Affinity
Purified rat conjugate antibody in buffer containing PBS (pH 7.2) with up to 0.1% sodium azide.

Storage and Stability

The antibody solution should be stored undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Lichen Zhang et al.
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