MABC82
Anti-RIP1/RIPK1 Antibody, clone 3C6.1
clone 3C6.1, from mouse
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Receptor-interacting serine/threonine-protein kinase 1, Cell death protein RIP, Receptor-interacting protein 1, RIP-1, Serine/threonine-protein kinase RIP
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biological source
mouse
Quality Level
antibody form
purified antibody
antibody product type
primary antibodies
clone
3C6.1, monoclonal
species reactivity
human
technique(s)
western blot: suitable
isotype
IgG2aκ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... RIPK1(8737)
General description
Receptor-interacting serine/threonine-protein kinase 1, also known as Cell death protein RIP or Receptor-interacting protein 1 (RIP-1) or Serine/threonine-protein kinase RIP, and encoded by the gene name RIPK1 or RIP or RIP1, contains 1 death domain and 1 protein kinase domain. RIPK1 is localized to the cytoplasm and plays an important role in a variety of cellular pathways including the NF-κB pathway and programmed necrotic cell death (necroptosis).
Immunogen
GST-tagged recombinant protein corresponding to human RIP1/RIPK1.
Application
Detect RIP1/RIPK1 using this Anti-RIP1/RIPK1 Antibody, clone 3C6.1 validated for use in western blotting.
Quality
Evaluated by Western Blotting in Jurkat cell lysate.
Western Blotting Analysis: 0.5 µg/mL of this antibody detected RIP1/RIPK1 in 200 µg of Jurkat cell lysate.
Western Blotting Analysis: 0.5 µg/mL of this antibody detected RIP1/RIPK1 in 200 µg of Jurkat cell lysate.
Target description
~ 76 kDa observed
Linkage
Replaces: MABC688
Physical form
Format: Purified
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
WGK
WGK 1
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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