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Key Documents

MABC538

Sigma-Aldrich

Anti-FANCJ/BACH1 Antibody, clone 2G7

clone 2G7, from mouse

Synonym(s):

Fanconi anemia group J protein, Protein FACJ, ATP-dependent RNA helicase BRIP1, BRCA1-associated C-terminal helicase 1, BRCA1-interacting protein C-terminal helicase 1, BRCA1-interacting protein 1

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100 μG
CN¥4,489.38

CN¥4,489.38

Estimated to ship onMay 12, 2025Details

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100 μG
CN¥4,489.38

About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

CN¥4,489.38

Estimated to ship onMay 12, 2025Details

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Request a Bulk Order

biological source

mouse

Quality Level

100

antibody form

purified antibody

antibody product type

primary antibodies

clone

2G7, monoclonal

species reactivity

human

technique(s)

immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG1κ

NCBI accession no.

NP_114432

UniProt accession no.

Q9BX63

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This Item
HPA005474B1310MABE1071
Anti-FANCJ/BACH1 Antibody, clone 2G7 clone 2G7, from mouse

MABC538

Anti-FANCJ/BACH1 Antibody, clone 2G7

Anti-BRIP1 antibody produced in rabbit Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

HPA005474

Anti-BRIP1 antibody produced in rabbit

Anti-BACH1 antibody produced in rabbit affinity isolated antibody, buffered aqueous solution

B1310

Anti-BACH1 antibody produced in rabbit

Anti-BAP1 Antibody, clone 1G8 clone 1G8, from mouse

MABE1071

Anti-BAP1 Antibody, clone 1G8

clone

2G7, monoclonal

clone

polyclonal

clone

polyclonal

clone

1G8, monoclonal

species reactivity

human

species reactivity

human

species reactivity

human

species reactivity

human

Gene Information

human ... BRIP1(83990)

Gene Information

human ... BRIP1(83990)

Gene Information

human ... BRIP1(83990)
mouse ... Brip1(237911)
rat ... Brip1(360588)

Gene Information

human ... BAP1(8314)

biological source

mouse

biological source

rabbit

biological source

rabbit

biological source

mouse

shipped in

wet ice

shipped in

wet ice

shipped in

dry ice

shipped in

ambient

General description

Bach1 and Bach2 constitute a subfamily of the basic region-leucine zipper family. Bach proteins form heterodimers with small Maf proteins, bind to the Maf recognition element (MARE) and repress target gene expression. Transcription regulator protein BACH2 mediates early B cell differentiation and is specifically expressed in pro and mature B-cells. This protein plays an important role in both the immunoglobulin class switch, oncogene-induced senescence, and somatic hypermutation.

Immunogen

Epitope: C-terminus
Linear peptide corresponding to the C-terminus of human FANCJ/BACH1.

Application

Immunocytochemistry Analysis: A representative lot from an independent laboratory detected FANCJ/BACH1 in MCF-7 cells (Cantor, S. B., et al. (2001). Cell. 105(1):149-160.).

Western Blotting Analysis: A representative lot from an independent laboratory detected FANCJ/BACH1 in transfected FA-J cell lysate (Xie, J., et al. (2010). Oncogene. 29(17):2499-2508.).

Immunoprecipitation Analysis: A representative lot from an independent laboratory immunoprecipitated FANCJ/BACH1 from MCF-7 cell lysate, prior to detecting the immunoprecipitated sample in Western Blot (Cantor, S. B., et al. (2001). Cell. 105(1):149-160.).
Research Category
Apoptosis & Cancer
Research Sub Category
Apoptosis - Additional
This Anti-FANCJ/BACH1 Antibody, clone 2G7 is validated for use in western blotting, ICC & IP for the detection of FANCJ/BACH1.

Quality

Evaluated by Western Blotting in MCF-7 cell lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected FANCJ/BACH1 in 10 µg of MCF-7 cell lysate.

Target description

~140 kDa observed

Physical form

Format: Purified
Protein G Purified
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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