MAB858-1
Anti-RSV Antibody, fusion protein, all type A, B strains, clone 133-1H
ascites fluid, clone 133-1H, from mouse
Synonym(s):
RSV
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
biological source
mouse
Quality Level
antibody form
ascites fluid
antibody product type
primary antibodies
clone
133-1H, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable
immunofluorescence: suitable
isotype
IgG2a
shipped in
wet ice
General description
RSV is a labile paramyxovirus that produces a characteristic fusion of human cells in tissue culture--the syncytial effect. Two subtypes, A and B, have been identified. Subtype B are characterized as the asymptomatic strains of the virus. The more severe clinical illnesses involve Subtype A strains.
Specificity
Directed against the 47-49 kDa Fusion Protein of RSV. Antibody MAB858-1 recognizes both A and B RSV strains.
Immunogen
A2
Epitope: all type A & B strains
Application
ELISA at 1:800+
Indirect Immunofluorescence at 1:100-200+ (fresh frozen tissue sections)
Final working dilutions must be determined by end user.
Indirect Immunofluorescence at 1:100-200+ (fresh frozen tissue sections)
Final working dilutions must be determined by end user.
Research Category
Infectious Diseases
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral
Infectious Diseases - Viral
This Anti-RSV Antibody, fusion protein, all type A, B strains, clone 133-1H is validated for use in ELISA, IF for the detection of Respiratory Syncytial Virus.
Physical form
Ascites fluid with 0.1% sodium azide as a preservative.
Unpurified
Storage and Stability
Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Analysis Note
Control
RSV Control Slides, Catalogue Number 5012-5
RSV Control Slides, Catalogue Number 5012-5
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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recommended
Storage Class Code
12 - Non Combustible Liquids
WGK
nwg
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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E K Park et al.
Molecules and cells, 12(1), 50-56 (2001-09-20)
Respiratory syncytial virus (RSV) is one of the principal agents of bronchiolitis and pneumonia in young children. Thus, there is a strong need to make a safe and effective vaccine against the RSV infection. DNA immunization is very effective at
Wy Ching Ng et al.
Journal of virology, 90(1), 206-221 (2015-10-16)
It is well established that influenza A virus (IAV) attachment to and infection of epithelial cells is dependent on sialic acid (SIA) at the cell surface, although the specific receptors that mediate IAV entry have not been defined and multiple
Bahar Ahani et al.
Nature communications, 14(1), 4347-4347 (2023-07-20)
Nirsevimab is a monoclonal antibody that binds to the respiratory syncytial virus (RSV) fusion protein. During the Phase 2b (NCT02878330) and MELODY (NCT03979313) clinical trials, infants received one dose of nirsevimab or placebo before their first RSV season. In this
Giulia Campanini et al.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 39(2), 119-124 (2007-04-25)
Human respiratory syncytial virus (hRSV) detection in nasopharyngeal aspirates (NPAs) from infants with acute respiratory tract infection (ARTI) does not prove the hRSV etiology of the current ARTI episode. HRSV RNA quantification may help in affording this issue. hRSV was
Bert Schepens et al.
EMBO molecular medicine, 6(11), 1436-1454 (2014-10-10)
Infections with human respiratory syncytial virus (HRSV) occur globally in all age groups and can have devastating consequences in young infants. We demonstrate that a vaccine based on the extracellular domain (SHe) of the small hydrophobic (SH) protein of HRSV
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