MAB8051
Anti-Adenovirus Antibody, clone 2/6
clone 2/6, Chemicon®, from mouse
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UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
mouse
Quality Level
antibody form
purified immunoglobulin
clone
2/6, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable
flow cytometry: suitable
immunofluorescence: suitable
immunohistochemistry: suitable
isotype
IgG1κ
shipped in
wet ice
General description
Adenoviruses are 65-80 nm, non-enveloped, regular icosahedron pathogens often associated with respiratory and gastrointestinal illness as well as conjunctivitis. Well over 40 types of adenoviruses have currently been recognized. In addition to their deleterious effects, adenoviruses have been used in vaccine production and in gene therapy. They also have the ability to trigger cell proliferation by interfering with host cellular anti-oncogenes. Since they are easy to prepare, multiple quickly and efficiently, and have the ability to infect and deliver their genome (including researcher-created constructs) to the nucleus of a variety of post-mitotic cells, adenoviruses are extremely valuable in research and medical applications ranging from virus/host cell interaction to the insertion of novel genes or regulatory mechanisms into eukaryotic cellular systems, to delivery of therapeutic anti-cancer genes.
Specificity
All 41 serotypes of Adenovirus.
Application
Detect Adenovirus using this Anti-Adenovirus Antibody, clone 2/6 validated for use in ELISA, FC, IF, IH.
ELISA
IFA: acetone fixed cell preparations or tissues.
FACS: {McNees, 2004}
Dilute with buffer pH 7.5-8.0 to desired working volume.
For extensive dilution, protein containing or other stabilizing medium should be used.
Final working dilutions must be determined by end user.
IFA: acetone fixed cell preparations or tissues.
FACS: {McNees, 2004}
Dilute with buffer pH 7.5-8.0 to desired working volume.
For extensive dilution, protein containing or other stabilizing medium should be used.
Final working dilutions must be determined by end user.
Physical form
Format: Purified
Protein A-purified immunoglobulin. Liquid at 1 mg/mL in 20 mM phosphate buffer, containing 25 mM NaCl and 0.1% sodium azide, pH 7.6
Storage and Stability
Maintain at 2-8°C in convenient aliquots for up to 12 months. Do not store in a diluted format.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Modeling adenovirus latency in human lymphocyte cell lines.
Zhang, Y; Huang, W; Ornelles, DA; Gooding, LR
Journal of virology null
Postinternalization inhibition of adenovirus gene expression and infectious virus production in human T-cell lines.
McNees, AL; Mahr, JA; Ornelles, D; Gooding, LR
Journal of virology null
An outbreak of epidemic keratoconjunctivitis in a regional ophthalmology clinic in New South Wales.
K A Viney,P J Kehoe,B Doyle,V Sheppeard,A R Roberts-Witteveen,H Semirli,K A McPhie et al.
Epidemiology and Infection null
Protein crystals in Adenovirus type 5-infected cells: requirements for intranuclear crystallogenesis, structural and functional analysis.
Franqueville, L; Henning, P; Magnusson, M; Vigne, E; Schoehn, G; Blair-Zajdel, ME; Habib et al.
Testing null
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