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MAB5778

Sigma-Aldrich

Anti-NMDAR2B Antibody, CT

ascites fluid, clone 1C6.5C4, Chemicon®

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UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

antibody form

ascites fluid

clone

1C6.5C4, monoclonal

species reactivity

human, rat, rabbit, mouse

manufacturer/tradename

Chemicon®

technique(s)

western blot: suitable

isotype

IgG1

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Specificity

NMDAR2B, C-terminal. By Western blot the antibody reacts with a band at ~170 kDa on rat brain lysate.

Immunogen

Recombinant protein from rat NMDAR2B.

Application

Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
This Anti-NMDAR2B Antibody, C-terminal is validated for use in WB for the detection of NMDAR2B.
Western blot: 1:100-1:1,000 on rat brain lysate.

Optimal working dilutions must be determined by end user.

Physical form

Ascites
Liquid ascites.

Storage and Stability

6 months at -20°C from date of shipment

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Kyeong-No Yoon et al.
The British journal of nutrition, 131(7), 1105-1114 (2023-11-29)
Brain ageing, the primary risk factor for cognitive impairment, occurs because of the accumulation of age-related neuropathologies. Identifying effective nutrients that increase cognitive function may help maintain brain health. Tomatoes and lemons have various bioactive functions and exert protective effects
Matthew T Swulius et al.
The Journal of comparative neurology, 518(20), 4243-4260 (2010-09-30)
In this study, we used electron tomography as well as immunogold labeling to analyze the morphology and distribution of proteins within postsynaptic densities (PSDs) isolated from rats before birth (embryonic day 19) and at postnatal days 2, 21, and 60.
GluN2B protein deficits in the left, but not the right, hippocampus in schizophrenia.
Geddes, AE; Huang, XF; Newell, KA
BMC Psychiatry null
Wenhui Qu et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 40(50), 9552-9563 (2020-11-04)
Triggering receptor expressed on myeloid cells 2 (TREM2), a receptor exclusively expressed by microglia in the brain, modulates microglial immune homeostasis. Human genetic studies have shown that the loss-of-function mutations in TREM2 signaling are strongly associated with an elevated risk
Marie Lise Frandemiche et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(17), 6084-6097 (2014-04-25)
Tau is a microtubule-associated protein well known for its stabilization of microtubules in axons. Recently, it has emerged that tau participates in synaptic function as part of the molecular pathway leading to amyloid-beta (Aβ)-driven synaptotoxicity in the context of Alzheimer's

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