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MAB5654

Sigma-Aldrich

Anti-Prox1 Antibody, clone 4G10

clone 4G10, Chemicon®, from mouse

Synonym(s):

Homeobox prospero-like protein PROX1

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

antibody form

purified antibody

antibody product type

primary antibodies

clone

4G10, monoclonal

species reactivity

chicken, mouse, rat, human, lizard

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable
western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

mouse ... Prox1(19130)

Related Categories

Specificity

Prox1. By Western blot the antibody recognizes a ~83 kDa protein in fetal mouse brain lysate.

Immunogen

Recombinant human Prox1 protein.

Application

Anti-Prox1 Antibody, clone 4G10 is an antibody against Prox1 for use in WB, IH.
Research Category
Neuroscience
Research Sub Category
Developmental Neuroscience

Neuronal & Glial Markers
Western blot: 2 μg/mL

Optimal working dilutions must be determined by end user.

Target description

83 kDa

Linkage

Replaces: MABE488

Physical form

Format: Purified
Liquid in PBS with 0.1% sodium azide.
Protein A purified

Storage and Stability

Maintain at 2-8degC in undiluted aliquots for up to 6 months after date of receipt.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Shogo Yoshihara et al.
Cell reports, 35(2), 108971-108971 (2021-04-15)
In schizophrenia (SCZ), neurons in the brain tend to undergo gross morphological changes, but the related molecular mechanism remains largely elusive. Using Kif3b+/- mice as a model with SCZ-like behaviors, we found that a high-betaine diet can significantly alleviate schizophrenic
Julia Holzmann et al.
Developmental neurobiology, 75(12), 1352-1367 (2015-03-20)
Neurogenesis in embryonic sympathetic ganglia involves neuroblasts that resume proliferation following neuronal differentiation. As cell cycle exit is not associated with neuronal differentiation, the identity of proliferating neuroblasts is incompletely understood. Here, we use sympathetic ganglia of chick embryos to
Rebecca S Lescarbeau et al.
Molecular cancer therapeutics, 15(6), 1332-1343 (2016-05-20)
Glioblastoma (GBM) is the most common malignant primary brain cancer. With a median survival of about a year, new approaches to treating this disease are necessary. To identify signaling molecules regulating GBM progression in a genetically engineered murine model of
Baptiste N Jaeger et al.
Nature communications, 9(1), 3084-3084 (2018-08-08)
Activity-induced remodeling of neuronal circuits is critical for memory formation. This process relies in part on transcription, but neither the rate of activity nor baseline transcription is equal across neuronal cell types. In this study, we isolated mouse hippocampal populations
Chih-Hao Yang et al.
Cell reports, 30(4), 959-968 (2020-01-30)
In the adult brain, new dentate granule cells integrate into neural circuits and participate in hippocampal functioning. However, when and how they initiate this integration remain poorly understood. Using retroviral and live-imaging methods, we find that new neurons undergo neurite remodeling for

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