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Merck
CN

MAB5296

Anti-Oxytocin Antibody, clone 4G11

ascites fluid, clone 4G11, Chemicon®

Synonym(s):

Anti-OT, Anti-OT-NPI, Anti-OXT-NPI

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
4G11, monoclonal
Application:
ELISA, IHC
Citations:
87

Key Documents

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biological source

mouse

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

4G11, monoclonal

species reactivity

rat, human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable, immunohistochemistry: suitable

isotype

IgG1

NCBI accession no.

NM_000915.2

UniProt accession no.

P01178

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... OXTR(5021)

Immunogen

Oxytocin conjugated to thyroglobulin.

Application

Immunohistochemistry on 4% paraformaldehyde fixed frozen tissue: 1:5,000-1:10,000.

ELISA: 1:1,000,000

Optimal working dilutions must be determined by the end user.
This Anti-Oxytocin Antibody, clone 4G11 is validated for use in ELISA, IH for the detection of Oxytocin.

Biochem/physiol Actions

Recognizes Oxytocin. No reactivity to arginine vasopressin, vasotocin or [Asu1,6,Arg8]-vasopressin by competitive ELISA.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Amy S Kohtz et al.
Psychopharmacology, 235(7), 2051-2063 (2018-04-20)
Initial drug abstinence (modeled here as Extinction Day 1, ED1) is a critical time point in the progression of addiction that is strongly influenced by stress and sex. ED1 induces corticosterone release in both sexes, and cocaine-seeking during ED1 can
Mamoru Tanida et al.
Diabetes, 64(11), 3725-3736 (2015-08-28)
Nesfatin-1 acts on the hypothalamus and regulates the autonomic nervous system. However, the hypothalamic mechanisms of nesfatin-1 on the autonomic nervous system are not well understood. In this study, we found that intracerebroventricular (ICV) administration of nesfatin-1 increased the extracellular
Mariela Mitre et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 36(8), 2517-2535 (2016-02-26)
Oxytocin is a neuropeptide important for social behaviors such as maternal care and parent-infant bonding. It is believed that oxytocin receptor signaling in the brain is critical for these behaviors, but it is unknown precisely when and where oxytocin receptors
Catherine E Barrett et al.
Neuropharmacology, 85, 357-366 (2014-06-14)
The melanocortin receptor (MCR) system has been studied extensively for its role in feeding and sexual behavior, but effects on social behavior have received little attention. α-MSH interacts with neural systems involved in sociality, including oxytocin, dopamine, and opioid systems.
Peimin Zhu et al.
The Journal of biological chemistry, 284(34), 22878-22887 (2009-06-23)
It is well established that CpG promotes pro-inflammatory cytokine and antibody production by B cells via the Toll-like receptor 9 (TLR9)-dependent pathway. However, scavenger receptors (SRs) are also capable of binding such pathogen-derived molecules, yet their contribution to CpG-induced signaling
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