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Merck
CN

MAB5220

Sigma-Aldrich

Anti-NMDAR2B Antibody, clone 13A11

clone 13A11, Chemicon®, from mouse

Synonym(s):

NR2B

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100 μL
CN¥4,239.58

CN¥4,239.58


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100 μL
CN¥4,239.58

About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

CN¥4,239.58


Please contact Customer Service for Availability
New, lower price on this item!

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biological source

mouse

Quality Level

antibody form

affinity purified immunoglobulin

clone

13A11, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

isotype

IgG1

NCBI accession no.

UniProt accession no.

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557324B9934G9420
利鲁唑 solid

R116

利鲁唑

Riluzole A cell-permeable benzothiazole compound that potently inhibits glutamate release and blocks Na+ channels.

557324

Riluzole

BTA-1 ≥98% (HPLC), solid

B9934

BTA-1

GNF-2 ≥98% (HPLC), solid

G9420

GNF-2

form

solid

form

solid

form

solid

form

solid

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

originator

Sanofi Aventis

originator

-

originator

-

originator

-

Gene Information

human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)
rat ... Scnn1g(24768)

Gene Information

-

Gene Information

human ... APP(351)

Gene Information

-

Specificity

NMDAR2B

Immunogen

Amino acid region 1033-1161 from human NMDAR2B produced as a GST fusion protein.

Application

Anti-NMDAR2B Antibody, clone 13A11 is an antibody against NMDAR2B for use in IC, IH & WB.
Immunohistochemistry (light and EM) on 4% paraformaldehyde & 0.125% glutaraldehyde fixed tissue: 2.5-5 μg/mL.

Immunocytochemistry: 2.5-5.0 μg/mL

Western blot: 1-5 μg/mL Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors

Physical form

Affinity purified immunoglobulin. Liquid in PBS. Contains no preservative.
Format: Purified

Storage and Stability

Maintain frozen at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Elisa A Waxman et al.
The Journal of biological chemistry, 282(24), 17594-17607 (2007-04-27)
The neuronal transporter excitatory amino acid carrier 1 (EAAC1) is enriched in perisynaptic regions, where it may regulate synaptic spillover of glutamate. In this study we examined potential interactions between EAAC1 and ionotropic glutamate receptors. N-Methyl-D-aspartate (NMDA) receptor subunits NR1
Sylvie L Lesuis et al.
Neuropharmacology, 149, 195-203 (2019-01-15)
Programming of the brain by early life stress has been associated with alterations in structure and function of the dorsal hippocampus. Yet, the underlying molecular mechanisms remain largely elusive. In this study, we examined the effects of early life stress
Alexandre A Hoeller et al.
PloS one, 11(1), e0147293-e0147293 (2016-01-23)
Extensive evidence indicates the influence of the cholinergic system on emotional processing. Previous findings provided new insights into the underlying mechanisms of long-term anxiety, showing that rats injected with a single systemic dose of pilocarpine--a muscarinic receptor (mAChR) agonist--displayed persistent
The N-methyl-D-aspartate receptor type 2A is frequently methylated in human colorectal carcinoma and suppresses cell growth.
Kim, MS; Chang, X; Nagpal, JK; Yamashita, K; Baek, JH; Dasgupta, S; Wu, G; Osada, M; Woo et al.
Oncogene null
Katherine Leaderbrand et al.
Neurobiology of learning and memory, 113, 35-40 (2013-09-24)
Unpredictable stress is known to profoundly enhance susceptibility to fear and anxiety while reducing the ability to extinguish fear when threat is no longer present. Accordingly, partial aversive reinforcement, via random exposure to footshocks, induces fear that is resistant to

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