MAB4369
Anti-SRF [Serum Response Factor] Antibody, clone 1E1
clone 1E1, from mouse
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Synonym(s):
serum response factor (c-fos serum response element-binding transcription factor)
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
mouse
antibody form
purified antibody
antibody product type
primary antibodies
clone
1E1, monoclonal
species reactivity
mouse, human
technique(s)
immunocytochemistry: suitable
western blot: suitable
input
sample type neural stem cell(s)
sample type mesenchymal stem cell(s)
isotype
IgG1κ
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... ELK3(2004)
General description
Serum response factor (SRF) is a nuclear transcription factor that binds to the serum response element (SRE), and is essential for embryonic development of the mesoderm, as well as for the maintenance of adult muscle cells and neurons. As this protein is involved in the downstream regulation of many immediate-early genes, it participates in a variety of cell functions, including cell cycle, apoptosis, cell growth, and cell differentiation. SRF is most commonly activated by serum, LPA, LPS, TPA, growth factors, including TNFalpha, as well as antioxidants and UV light.
Specificity
A weak interaction with mouse has also been observed. Reactivity with other species has not been tested.
This monoclonal antibody recognizes SRF.
Immunogen
Synthetic human SRF peptide, a.a. 406-508.
Application
Detect SRF [Serum Response Factor] using this Anti-SRF [Serum Response Factor] Antibody, clone 1E1 validated for use in WB & IC.
Immunocytochemistry: Recommended working dilution is 1:500.
Research Category
Stem Cell Research
Stem Cell Research
Research Sub Category
Mesenchymal Stem Cells
Neural Stem Cells
Mesenchymal Stem Cells
Neural Stem Cells
Quality
(Based upon representative data from a previous lot).
Western Blotting: Recommended working dilution is 0.5 µg/mL.
Western Blotting: Recommended working dilution is 0.5 µg/mL.
Target description
~52 kDa
Physical form
Format: Purified
Protein G Purified
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl, and 0.05% sodium azide.
Storage and Stability
Maintain refrigerated at 2-8°C in undiluted aliquots for up to 12 months. Avoid repeat freeze/thaw cycles.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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