Skip to Content
Merck
CN
All Photos(1)

Key Documents

MAB3126

Sigma-Aldrich

Anti-Calnexin Antibody, ER marker, clone C8.B6

ascites fluid, clone C8.B6, Chemicon®

Synonym(s):

IP90 Protein, Integral Membrane Protein IP90, Phosphoprotein pp90

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

100

antibody form

ascites fluid

antibody product type

primary antibodies

clone

C8.B6, monoclonal

species reactivity

mouse, human

manufacturer/tradename

Chemicon®

technique(s)

immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG1

NCBI accession no.

NM_001024649.1
NM_001746.3

UniProt accession no.

P27824

shipped in

dry ice

Gene Information

human ... CANX(821)

General description

Calnexin is a Ca++ binding protein found in endoplasmic reticulum membranes that binds to specific n-linked oligosaccharides found on newly synthesized proteins. It may play role in protein folding or retention and degradation of misfolded proteins in the endoplasmic reticulum.

Specificity

Recognizes Calnexin.

Immunogen

Epitope: ER marker
Recombinant human calnexin

Application

Detect Calnexin using this Anti-Calnexin Antibody, ER marker, clone C8.B6 validated for use in IC, IH, IP & WB.
Immunohistochemistry on frozen tissue sections: 1:500-1:2,000

Immunocytochemistry: 1:100--1:250

Immunoblotting: 1:200-1:2,000

Immunoprecipitation: 1:200-1:1,000

Optimal working dilutions must be determined by end user.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Not finding the right product?  

Try our Product Selector Tool.

recommended

Product No.
Description
Pricing

Storage Class Code

10-13 - German Storage Class 10 to 13

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

A heterozygous deletion mutation in the cardiac sodium channel gene SCN5A with loss- and gain-of-function characteristics manifests as isolated conduction disease, without signs of Brugada or long QT syndrome.
Zumhagen, S; Veldkamp, MW; Stallmeyer, B; Baartscheer, A; Eckardt, L; Paul, M; Remme et al.
Testing null
Rossella Titone et al.
Scientific reports, 8(1), 4378-4378 (2018-03-14)
Insulin and insulin-like growth factor-1 (IGF-1) are present in human tears and likely play an important role in mediating ocular surface homeostasis. We previously characterized the IGF-1/insulin hybrid receptor (Hybrid-R) in corneal epithelial cells and found that it was activated
Novel APP/A? mutation K16N produces highly toxic heteromeric A? oligomers.
Kaden, D; Harmeier, A; Weise, C; Munter, LM; Althoff, V; Rost, BR; Hildebrand et al.
EMBO Molecular Medicine null
Sharon O'Neill et al.
The Journal of biological chemistry, 293(23), 8750-8760 (2018-04-21)
Protein-protein interactions critically regulate many biological systems, but quantifying functional assembly of multipass membrane complexes in their native context is still challenging. Here, we combined modeling-assisted protein modification and information from human disease variants with a minimal-size fusion tag, split-luciferase-based
iTRAQ-based proteomics profiling reveals increased metabolic activity and cellular cross-talk in angiogenic compared with invasive glioblastoma phenotype.
Rajcevic, U; Petersen, K; Knol, JC; Loos, M; Bougnaud, S; Klychnikov, O; Li, KW; Pham et al.
Molecular and Cellular Proteomics null
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service