MAB2154
Anti-P-Selectin Antibody, clone P8G6
clone P8G6, Chemicon®, from mouse
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CD62P, Granule Membrane Protein-140, GMP-140, Platelet Activation Dependent Granule-external Membrane Protein, PADGEM
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biological source
mouse
Quality Level
antibody form
purified antibody
antibody product type
primary antibodies
clone
P8G6, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... SELP(6403)
Specificity
Human P Selectin
Immunogen
IL-1beta activated HUVEC (human)
Application
Detect P-Selectin using this Anti-P-Selectin Antibody, clone P8G6 validated for use in ELISA, IP, IC, IH.
Immunohistochemistry: for use on acetone or paraformaldehyde fixed tissue
Immunocytochemistry
Immunoprecipitation
ELISA
Inhibits P Selectin dependent interactions
Inhibits platelet binding to monocytes
Optimal working dilutions must be determined by end user.
Immunocytochemistry
Immunoprecipitation
ELISA
Inhibits P Selectin dependent interactions
Inhibits platelet binding to monocytes
Optimal working dilutions must be determined by end user.
Research Category
Cell Structure
Cell Structure
Research Sub Category
Adhesion (CAMs)
Adhesion (CAMs)
Physical form
Format: Purified
Purified in 0.02M PBS, 0.25M NaCl, pH 7.6 with 0.1% NaN3. Liquid
Storage and Stability
Maintain at 2-8°C in undiluted aliquots for up to 6 months.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Circulation, 110(17), 2713-2720 (2004-10-20)
Plasma C-reactive protein (CRP) level is a powerful predictor of cardiovascular events. However, it is not known whether CRP could affect neutrophil-platelet adhesion and neutrophil aggregation, key events in acute coronary syndromes. Emerging in vitro evidence suggests that some bioactivities
Journal of virology, 90(4), 1812-1823 (2015-12-08)
Lung injury after influenza infection is characterized by increased permeability of the lung microvasculature, culminating in acute respiratory failure. Platelets interact with activated endothelial cells and have been implicated in the pathogenesis of some forms of acute lung injury. Autopsy
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