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HNDG3MAG-36K

Millipore

MILLIPLEX® Human Neurodegenerative Disease Magnetic Bead Panel 3 - Neuroscience Multiplex Assay

The analytes available for this multiplex kit are: BDNF, Cathepsin D, MPO, NCAM, PAI-1 (total), PDGF-AA, PDGF-AB/BB, RANTES, sICAM-1, sVCAM-1.

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Synonym(s):
Human NeuroscienceProtein MultiplexAssay, Luminex® Human Neuroscience Panel, Millipore Human Neuroscience Immunoassay
UNSPSC Code:
12161503
eCl@ss:
32161000
NACRES:
NA.84

Quality Level

200

species reactivity

human

manufacturer/tradename

Milliplex®

assay range

accuracy: 108%
(RANTES)
accuracy: 108%
(sICAM-1)
accuracy: 111%
(Cathepsin D)
accuracy: 123%
(PDGF-AA)
accuracy: 137%
(PDGF-AB/BB)
standard curve range: 2-10,000 pg/mL
(RANTES)
standard curve range: 2.4-10,000 pg/mL
(BDNF)
standard curve range: 2.4-10,000 pg/mL
(PAI-1 (total))
standard curve range: 2.4-10,000 pg/mL
(PDGF-AA)
standard curve range: 24-100,000 pg/mL
(Cathepsin D)
standard curve range: 24-100,000 pg/mL
(MPO)
standard curve range: 24-100,000 pg/mL
(NCAM)
standard curve range: 24-100,000 pg/mL
(PDGF-AB/BB)
standard curve range: 24-100,000 pg/mL
(sICAM-1)
standard curve range: 61-250,000 pg/mL
(sVCAM-1)

technique(s)

multiplexing: suitable

detection method

fluorometric (Luminex xMAP)

shipped in

wet ice

Related Categories

General description

The MILLIPLEX® Human Neurodegenerative Bead Panel 3 (HNDG3MAG-36K) is to be used for the simultaneous quantification of the following 10 analytes in any combination: BDNF, Cathepsin D, MPO, NCAM, PAI-1 (total), PDGF-AA, PDGF-AB/BB, RANTES, sICAM-1, and sVCAM-1. This kit may be used for the analysis of all above analytes in human serum, plasma, and cerebrospinal fluid samples.

Panel Type: Neuroscience

Specificity

Cross Reactivty
Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.

Application

  • Analytes: BDNF, Cathepsin D, MPO, NCAM, PAI-1 (total), PDGF-AA, PDGF-AB/BB, RANTES, sICAM-1, sVCAM-1
  • Recommended Sample type: Serum, plasma, or CSF
  • Recommended Sample dilution: 1:100 diluted serum/plasma or neat CSF
  • Assay Run Time: Overnight
  • Research Category: Neuroscience
  • Research Subcategory: Category Alzheimer′s Disease Nervous System Neurodegenerative Diseases

Features and Benefits

Design your multiplex kit by choosing available analytes within this panel.

Packaging

Everything you need in a single kit.

Storage and Stability

Recommended storage for kit components is 2 - 8°C.

Other Notes

Sensitivity: See kit protocol for individual sensitvities

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2

Target Organs

Respiratory Tract

WGK

WGK 3

Regulatory Information

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Luís F Martins et al.
Scientific reports, 7(1), 4153-4153 (2017-06-25)
Mesenchymal stem cells (MSCs) have been used for cell-based therapies in regenerative medicine, with increasing importance in central and peripheral nervous system repair. However, MSCs grafting present disadvantages, such as, a high number of cells required for transplantation and low
Rong Ma et al.
OncoTargets and therapy, 13, 1883-1892 (2020-03-19)
This study aimed to investigate the diagnosis and prediction of serum platelet-derived growth factor (PDGF) level in patients with lung cancer (LC). Serum concentrations of PDGF-AA and PDGF-AB/BB were determined via Luminex assay in 210 patients with non-small cell lung
Rodrigo B Mansur et al.
Bipolar disorders, 18(5), 433-439 (2016-08-05)
Accumulating evidence indicates that oxidative stress and neurotrophins have a bidirectional relationship. In this post hoc, exploratory analysis, we investigated the association between plasma brain-derived neurotrophic factor (BDNF) levels and activities of the antioxidant enzymes glutathione peroxidase (GPx) and superoxide
Carolina Segura et al.
Frontiers in neurology, 11, 656-656 (2020-08-15)
Rationale: The optimal modality, intensity, duration, frequency, and dose-response of exercise as a therapy for Parkinson's Disease (PD) are insufficiently understood. Objective: To assess the impact of a high-intensity tandem bicycle program on clinical severity, biomarkers, and functional MRI (fMRI)
Maren S Fragala et al.
Journal of strength and conditioning research, 28(8), 2079-2087 (2014-05-17)
Aerobic exercise has been shown to counteract age-related neurological decrements that are associated with cognitive and physical impairments. However, the effects of resistance exercise on cognition, reaction, and neurotrophins are largely unknown. We examined changes in spatial awareness, visual and
View All Related Papers

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