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Merck
CN

HCDC0001L102

Millipore

Mobius Gold High Cell Density Cryopreservation Assembly

(-80C), 250 mL, sterile; γ-irradiated (at 25-40 kGy)

Synonym(s):

Mobius® Gold High Cell Density Cryopreservation Assembly (-80C), 250 mL

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500 G
CN¥2,444.35

CN¥2,444.35


Available to ship onApril 23, 2025Details



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500 G
CN¥2,444.35

About This Item

UNSPSC Code:
41103801

CN¥2,444.35


Available to ship onApril 23, 2025Details


material

device (thermoplastic elastomer)
polyethylene device
polypropylene device
silicone device

Quality Level

Agency

according to ISO 11137
meets EN 2.6.14
meets JP 4.01
meets USP 85

sterility

sterile; γ-irradiated (at 25-40 kGy)

product line

Mobius®

parameter

-80-60 °C temp. range (-112-140 °F)
0.3 bar max. pressure (4.4 psi)
150 mL process volume

capacity

250 mL

impurities

<0.25 EU/mL Aqueous extraction (LAL test)

application(s)

mAb

storage temp.

2-30°C

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This Item
D5287D7400B5002
Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

assay

≥98.5%

assay

≥98%

assay

≥99%

assay

≥99% (HPLC)

form

powder

form

powder

form

powder

form

powder

solubility

water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

solubility

1 M NH4OH: 50 mg/mL, clear, colorless

solubility

water: 25 mg/mL, clear to slightly hazy, colorless to faintly yellow

solubility

DMSO: 50 mg/mL, clear, colorless to very faintly yellow

impurities

Thymidine, free

impurities

inosine, essentially free

impurities

-

impurities

-

General description

Device configuration: 5 bags per assembly
Device configuration: 5 bags per assembly
Our Mobius® High Cell Density Cryopreservation (HCDC) Assembly (-196C) is a single-use assembly specially designed to facilitate the freeze and thaw of cryopreserved cells in liquid nitrogen vapor phase (? -196°C). Available in two assembly bag sizes of 100 mL and 250 mL, our Mobius® HCDC Assembly (-196C) enables seed train inoculation with cells at a higher cell density and larger volume compared to the traditional seed train process using vials, which significantly accelerates the cell expansion process. Our Mobius® single-use assembly also provides a closed processing environment preventing contamination while improving process reproducibility.
Our Mobius® High Cell Density Cryopreservation (HCDC) Assembly (-80°C) is a single-use assembly specially designed to facilitate the freeze and thaw of cryopreserved cells at -80°C. Available in two assembly bag sizes of 100 mL and 250 mL, our Mobius® HCDC Assembly (-80°C) enables seed train inoculation with cells at a higher cell density and larger volume compared to the traditional seed train process using vials, which significantly accelerates the cell expansion process. Our Mobius® single-use assembly also provides a closed processing environment preventing contamination while improving process reproducibility.

Specificity

All component materials, in contact with sampling liquid, meet the criteria for Class VI testing based on USP <88> Biological Reactivity, in vivo.
All component materials, in contact with sampling liquid, meet the criteria for Class VI testing based on USP <88> Biological Reactivity, in vivo.
Application

Application

Croyopreserved storage of cells

Packaging

Five (5) assembies per package with each assembly containing five (5) 100 mL cryo bags
Five (5) assembies per package with each assembly containing five (5) 250 mL cryo bags

Components

Fluoropolymer bags: Tubing: Silicone and Thermoplastic ElastomerFittings: PolypropyleneNovaSeal Pinch Pipes: Nickel plated brass
Pinch clamp: Nylon
Polyethylene bags: Pureflex FilmTubing: Silicone and Thermoplastic ElastomerFittings: PolypropyleneNovaSeal Pinch Pipes: Nickel plated brassPinch clamp: Nylon

Other Notes

Bags manufactured under ISO Clean Room Class 8 conditions in a facility certified to ISO 14644-1 standards. Assembly performed under ISO Clean Room Class 7 conditions in a facility certified to ISO 14644-1 standards.
Bags manufactured under ISO Clean Room Class 8 conditions in a facility certified to ISO 14644-1 standards. Assembly performed under ISO Clean Room Class 7 conditions in a facility certified to ISO 14644-1 standards.

Legal Information

MOBIUS is a registered trademark of Merck KGaA, Darmstadt, Germany

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Regulatory Information

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Articles

Understand how considerations such as DMSO concentrations and freezing techniques are key in the successful implementation of high cell density cryopreservation (HCDC).

High cell density cryopreservation (HCDC) is a closed processing alternative to the traditional seed train expansion process. Learn more about the benefits of HCDC.

This page provides an overview of USP <87>, <88>, and <1031>, compares bioreactivity testing, and describes the transition of our organization towards in vitro test methods.

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