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Milli-Q

Biopak® Polisher

Ultrafilter for the production of pyrogen-, nuclease-, protease- and bacteria-free water at the point of dispense of Milli-Q® IQ/IX/EQ systems

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About This Item

UNSPSC Code:
41104212
eCl@ss:
33050190
NACRES:
JA.13

material

polysulfone filter

Quality Level

300

packaging

pkg of 1 unit

manufacturer/tradename

BioPak®

technique(s)

ELISA: suitable
PCR: suitable
cell culture | mammalian: suitable

compatibility

for use with Milli-Q® EQ 7000
for use with Milli-Q® EQ 7008
for use with Milli-Q® EQ 7016
for use with Milli-Q® IX 7003
for use with Milli-Q® IX 7005
for use with Milli-Q® IX 7010
for use with Milli-Q® IX 7015
for use with Milli-Q® IQ 7000
for use with Milli-Q® IQ 7003
for use with Milli-Q® IQ 7005
for use with Milli-Q® IQ 7010
for use with Milli-Q® IQ 7015

shipped in

ambient

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General description

The Biopak® Polisher is an ultrafiltration cartridge designed to produce water suitable for molecular biology, biochemistry and cell culture when fed with Milli-Q® purified water. It is validated for continuous use for 90 days.

Application

Biopak® Polisher ultrafiltration cartridge is suitable for use with Milli-Q® IX 7003/05/10/15, Milli-Q® IQ 7000, Milli-Q® IQ 7003/05/10/15, Milli-Q® EQ 7000 and Milli-Q® EQ 7008/16 water purification systems.. Designed for applications such as molecular biology, biochemistry and cell culture (when fed with Milli-Q® purified water), the Biopak® ultrafiltration unit removes macromolecules and larger biological structures, such as bacteria.

Biopak® Polisher is recommended for a wide range of laboratory applications where bacteria, pyrogen, nuclease and/or protease levels must be controlled.
This includes small-interfering RNA (siRNA) research, RNA in situ hybridization, microarray development, or studies of protein synthesis machinery.

Features and Benefits

  • Minimizes risk of nuclease, protease, pyrogen or bacteria contamination.
  • Eliminates the need for toxic agents such as DEPC, therefore improving safety, saving time and reducing costs.
  • Bottom-tip is redesigned for a secured installation of the protection bell.
  • Easy maintenance: the polisher is easily installed and replaced; does not require sanitization.
  • e-Sure tag for RFID connection with POD enables full traceability (data management) and automatic consumable status monitoring on the POD′s touchscreen interface.

Other Notes

Directions For Use
Organism Retention: Bacteria and pyrogens
Mode of Action: Ultrafiltration
Application: Cell culture media, molecular biology
Intended Use: Bioburden reduction
Instructions for Use: This item provides water filtered through ultrafiltration hollow fibers. Refer to insert, section "replacement" in the product package.
Storage Statement: Store in dry location.
Disposal Statement: Dispose of in accordance with applicable federal, state and local regulations.
  • Pyrogens (endotoxins) < 0.001 EU/mL
  • RNases < 1 pg/mL
  • DNases < 5 pg/mL
  • Protease < 0.15 μg/mL
  • Bacteria < 0.01 CFU/mL

Legal Information

BIOPAK is a registered trademark of Merck KGaA, Darmstadt, Germany
Milli-Q is a registered trademark of Merck KGaA, Darmstadt, Germany

also commonly purchased with this product

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Description
Pricing

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Milli-Q® IQ 7000 Ultrapure Water Purification System, output: type 1 water (18.2 MΩ·cm), the most advanced Milli-Q® ultrapure (Type 1) water purification system that is intelligent, intuitive, and green.

ZIQ7003T0C

Milli-Q® IQ 7003 Ultrapure and Pure Water Purification System, Produces ultrapure (Type 1) water and pure (Type 2) water with a production flow rate of 3 L/hr from tap water feed

ZIQ7005T0C

Milli-Q® IQ 7005 Ultrapure and Pure Water Purification System, Produces ultrapure (Type 1) water and pure (Type 2) water with a production flow rate of 5 L/hr from tap water feed.

ZIQ7010T0C

Milli-Q® IQ 7010 Ultrapure and Pure Water Purification System, Produces ultrapure (Type 1) water and pure (Type 2) water with a production flow rate of 10 L/hr from tap water feed.

ZIQ7015T0C

Milli-Q® IQ 7015 Ultrapure and Pure Water Purification System, Produces ultrapure (Type 1) water and pure (Type 2) water with a production flow rate of 15 L/hr from tap water feed.

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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  1. How frequently do the various consumables need to be changed?

    The frequency that consumables must be changed depends on the system's usage (treated water volume) and on the consumables themselves (time of usage). In order to ensure the quality of water and your results, the consumables should be replaced when the system alerts you.

  2. What is the consumables delivery time?

    Refer to the consumable's Product page for a first estimation of its expected delivery time and contact customer service for more information.

  3. How are consumables changed?

    To help you to change your system's consumables, several video tutorials are available on our YouTube channel: Milli-Q®System Care Tutorials. For high-flow systems, please keep in mind that all consumable changes must be approved by a 3-digit code that only the person in charge of the system knows.

  4. What is the shelf life for Filter?

    The shelf life is 2 years for all consumables kept in the recommended storage conditions (temperatures from 5 to 30°C; humidity between 10 and 80%). Contact your local representative for more information.

  5. Can I arrange to have my consumables automatically ordered and delivered once a year?

    It's possible to place only one consumable order per year with a specific contract called "Consumable Supply Agreement (CSA)" For further information, contact your local representative or sales contact.

  6. Where can I find data sheets, Certificates of Origin, Certificates of Analysis, and Certificates of Quality?

    Documents and certificates are available in the "Documentation" section on this page. Do not hesitate to contact us if you require further information.

  7. What steps are you taking towards improved sustainability?

    Sustainability is at the heart of our innovations. From reducing water and energy consumption, to minimizing plastic and chemical waste, our dedicated water system engineers are constantly working on new ways to reduce the ecological footprint of our products to better support the sustainability goals we’re all striving towards. For more information, we invite you to review the following brochure and infographic which highlight our efforts and achievements: link. Do not hesitate to contact your local representative for further information.

  8. How can I know which consumables can be used with my system?

    To know which consumables can be used on your system, you can see in the user manual of you system or see it on the following webpage of consumables. All the consumables for each system are indicated.

  9. If I have a final filter that I use only occasionally (e.g., Biopak®) and have another filter (e.g. Millipak®) that I most of the time, can I keep the 'occasional-use' filter for use again at a later time?

    It is not possible to re-use a filter that has been used and then removed because air intake during replacement creates an airlock and blocks water passing through the filter. If you regularly need two different filters, we recommend using two POD dispensers.

  10. Can consumables be opened and refilled?

    Unfortunately, this is not possible because of safety issues and the need to guarantee the quality of consumables and their interior purification components. Our consumables are manufactured in an ISO 9001-certified facility France in agreement with high quality standards.

Real-time assay for testing components of protein synthesis
Rosenblum G, et al.
Nucleic Acids Research, 40(12), e88-e88 (2012)
Andrea Bleckmann et al.
Methods in molecular biology (Clifton, N.J.), 1669, 159-171 (2017-09-25)
A key element to understand developmental and reproductive processes like germline development, double fertilization, and embryogenesis is the study of cell-specific gene expression patterns which is best analyzed by RNA in situ hybridization. Different visualization techniques have been established to
Detection and Quantification of MicroRNAs by Ligase-Assisted Sandwich Hybridization on a Microarray
Iizuka R, et al.
Microarrays, 1368 (2016)
Giacomo Reina et al.
Nanoscale, 10(13), 5965-5974 (2018-03-16)
Several studies have demonstrated the ability of graphene oxide (GO) to efficiently adsorb small-interfering RNA (siRNA) on its surface and to transport it into cells. However, studies on whether and how siRNA interacts with GO are still inconclusive. In this
Whole mount RNA-FISH on ovules and developing seeds
Bleckmann A and Dresselhaus T
Chemosphere, 159-171 (2017)
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Water for PCR Techniques

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Water for Nuclease-sensitive Molecular Biology Studies

Nuclease-free water (or PCR water) is needed in molecular biology to avoid sample degradation during PCR, sequencing, etc. Ultrafiltration provides a quicker, safer, and more sustainable alternative to DEPC treatment when preparing RNase-free and DNase-free water.

Ultrapure Water for BPA-free Culture Media

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Milli-Q® Ultrapure Water Solutions

Milli-Q® ultrapure water systems ensure reliable science, with an expanded system offer catering to diverse lab needs and constraints.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service