Skip to Content
Merck
CN
All Photos(1)

Documents

CDUFBI001

Milli-Q

Biopak® Polisher

Ultrafilter for the production of pyrogen-, nuclease-, and bacteria-free water

Sign Into View Organizational & Contract Pricing


About This Item

UNSPSC Code:
41104212
eCl@ss:
33050190
NACRES:
NA.21

material

polysulfone (Ultrafiltration Hollow Fibers)

Quality Level

feature

removal of pyrogen (endotoxins), nuclease and bacteria in water

packaging

pkg of 1 unit

manufacturer/tradename

BioPak®

impurities

<0.001 EU/mL Pyrogens (endotoxins)
<0.01 ng/mL RNases
<0.1 cfu/mL Bacteria
<4 pg/μL DNases

compatibility

for use with Direct-Q® UV
for use with Direct-Q®
for use with Elix® Advantage
for use with Milli-Q® Direct
for use with Milli-Q® Reference
for use with Simplicity® UV
for use with Simplicity®
for use with Synergy® UV
for use with Synergy®

shipped in

ambient

Looking for similar products? Visit Product Comparison Guide

General description

The Biopak® Polisher is an ultrafiltration cartridge designed to produce water suitable for molecular biology, biochemistry and cell culture when fed with Milli-Q® purified water. It is validated for continuous use for 90 days.

Application

Biopak® Polisher is recommended for a wide range of laboratory applications such as molecular biology, cell culture and biochemistry, where bacteria, pyrogen and/or nuclease levels must be controlled. This includes bloodstream bacterial infections (BSIs) research, electrochemical biosensor development, endotoxin adsorption studies, antimicrobial testing and mRNA and protein detection.

Features and Benefits

  • Minimizes risk of nuclease, pyrogen and bacteria contamination.
  • Eliminates the need for toxic agents such as DEPC, therefore improving safety, saving time and reducing costs.
  • Care-free maintenance: The polisher is easily installed and replaced; does not require sanitization.

Components

Ultrafiltation hollow fibers

Other Notes

Directions for Use

  • Organism Retention: Bacteria and pyrogens
  • Mode of Action: Ultrafiltration
  • Application: Cell culture media, molecular biology
  • Intended Use: Bioburden reduction
  • Instructions for Use: This item provides water filtered through ultrafiltration hollow fibers. Refer to insert, section "replacement" in the product package.
  • Storage Statement: Store in a dry location.
  • Disposal Statement: Dispose of in accordance with applicable federal, state and local regulations.

Legal Information

BIOPAK is a registered trademark of Merck KGaA, Darmstadt, Germany
DIRECT-Q is a registered trademark of Merck KGaA, Darmstadt, Germany
ELIX is a registered trademark of Merck KGaA, Darmstadt, Germany
Milli-Q is a registered trademark of Merck KGaA, Darmstadt, Germany
SIMPLICITY is a registered trademark of Merck KGaA, Darmstadt, Germany
SYNERGY is a registered trademark of Merck KGaA, Darmstadt, Germany

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

  1. How frequently do the various consumables need to be changed?

    The frequency that consumables must be changed depends on the system's usage (treated water volume) and on the consumables themselves (time of usage). In order to ensure the quality of water and your results, the consumables should be replaced when the system alerts you.

  2. What is the consumables delivery time?

    Refer to the consumable's Product page for a first estimation of its expected delivery time and contact customer service for more information.

  3. How are consumables changed?

    To help you to change your system's consumables, several video tutorials are available on our YouTube channel: Milli-Q®System Care Tutorials. For high-flow systems, please keep in mind that all consumable changes must be approved by a 3-digit code that only the person in charge of the system knows.

  4. What is the shelf life for Filter?

    The shelf life is 2 years for all consumables kept in the recommended storage conditions (temperatures from 5 to 30°C; humidity between 10 and 80%). Contact your local representative for more information.

  5. Can I arrange to have my consumables automatically ordered and delivered once a year?

    It's possible to place only one consumable order per year with a specific contract called "Consumable Supply Agreement (CSA)" For further information, contact your local representative or sales contact.

  6. Where can I find data sheets, Certificates of Origin, Certificates of Analysis, and Certificates of Quality?

    Documents and certificates are available in the "Documentation" section on this page. Do not hesitate to contact us if you require further information.

  7. What steps are you taking towards improved sustainability?

    Sustainability is at the heart of our innovations. From reducing water and energy consumption, to minimizing plastic and chemical waste, our dedicated water system engineers are constantly working on new ways to reduce the ecological footprint of our products to better support the sustainability goals we’re all striving towards. For more information, we invite you to review the following brochure and infographic which highlight our efforts and achievements: link. Do not hesitate to contact your local representative for further information.

  8. How can I know which consumables can be used with my system?

    To know which consumables can be used on your system, you can see in the user manual of you system or see it on the following webpage of consumables. All the consumables for each system are indicated.

  9. If I have a final filter that I use only occasionally (e.g., Biopak®) and have another filter (e.g. Millipak®) that I most of the time, can I keep the 'occasional-use' filter for use again at a later time?

    It is not possible to re-use a filter that has been used and then removed because air intake during replacement creates an airlock and blocks water passing through the filter. If you regularly need two different filters, we recommend using two POD dispensers.

  10. Can consumables be opened and refilled?

    Unfortunately, this is not possible because of safety issues and the need to guarantee the quality of consumables and their interior purification components. Our consumables are manufactured in an ISO 9001-certified facility France in agreement with high quality standards.

The importance of the assembling of DNA strands on the performance of electrochemical genosensors
Batistuti MR, et al.
Microchemical Journal, Devoted to the Application of Microtechniques in All Branches of Science, 159, 105358-105358 (2020)
Explicit measurement of the endotoxin adsorption efficiency detects non-Langmuir behavior at low concentrations
Kholina EG, et al.
Analytical biochemistry, 587, 113445-113445 (2019)
FISH-Flow, a protocol for the concurrent detection of mRNA and protein in single cells using fluorescence in situ hybridization and flow cytometry
Arrigucci R, et al.
Nature Protocols, 12(6), 1245-1260 (2017)
A Flowthrough Assay for Rapid Bedside Stratification of
Bloodstream Bacterial Infection in Critically Ill Patients: a Pilot
Study
Jagtap P, et al.
Journal of Clinical Microbiology, 56(9), e00408-e00418 (2018)
Tandem malonate-based glucosides (TMGs) for membrane protein structural studies
Hussain H, et al.
Scientific reports, 7(1), 1-11 (2017)

Articles

Nuclease-free water (or PCR water) is needed in molecular biology to avoid sample degradation during PCR, sequencing, etc. Ultrafiltration provides a quicker, safer, and more sustainable alternative to DEPC treatment when preparing RNase-free and DNase-free water.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service