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C5VP380A

Millipore

Cellicon® Filter Assembly with Durapore® Membrane

filtration area 3.8 m2

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Synonym(s):
Cellicon® Filter Assembly with Durapore® Membrane

material

PVDF membrane
polyester screen
polypropylene housing (polypropylene silicone)
silicone O-ring

sterility

non-sterile; γ-irradiated

storage condition

dry at room temperature
room temperature (15-30°C)

parameter

7.37 L/min-m2 flow rate

technique(s)

tangential flow filtration (TFF): suitable

D × W × H

33.0 cm (13.0 in) × 23.4 cm (9.2 in) × 37.6 cm (14.8 in)

filtration area

3.8 m2

volume

3.5 L , Filter Only
3500 mL
4.1 L , Assembly
41000 mL

matrix

Durapore®

pore size

5.0 μm

pH

4-8

application(s)

mAb
recombinant protein

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General description

The Cellicon® Filter Assembly is designed to meet your perfused seed train challenges. It is a flat sheet cell retention filter running in tangential flow filtration mode part of a single-use assembly. Perfusion operations deliver high-density cell cultures that alleviate the burden of processing large production bioreactor volumes while increasing manufacturing flexibility. Introducing perfusion to your seed train makes it possible to inoculate a higher quantity of cells for one or more production bioreactors, thus increasing process efficiency.

Application

Microfiltration and Seed Train Perfusion

Features and Benefits

  • Predictable linear scalability from lab to manufacturing scale
  • Reliable and reproducible performance
  • Gentle on cells, maximizing cell density and viability
  • Easy installation, with smooth connection to bioreactor through welding or sterile connectors


Packaging

The Cellicon® filter packaging meets the requirements of the American Society for Testing and Materials (ASTM) Integrity Test Procedure D4169. The Cellicon® filter and assembly are secured in foam parts which is then double bagged. A caution label and a gamma indicator label are included on the inner bag. The double bagged Cellicon® filter Assembly is individually boxed. A Certificate of Quality is available electronically.

Other Notes

The Emprove® Program complements the product portfolio through comprehensive documentation to support qualification, risk assessment and process optimization needs.
Consolidation of product specific testing, quality and regulatory information to simplify compliance requirements.
Convenient 24/7 access to up-to-date product information.

Legal Information

CELLICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Durapore is a registered trademark of Merck KGaA, Darmstadt, Germany
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

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