BI0158
Activator Reagent 0.5M ETT in Acetonitrile
0.5M ETT in Acetonitrile
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About This Item
UNSPSC Code:
41116006
Quality Level
200
300
product line
Novabiochem®
form
liquid
reaction suitability
reaction type: Coupling Reactions
reagent type: catalyst
transition temp
flash point 5.6 °C
shipped in
ambient
storage temp.
2-30°C
Related Categories
Application
Ethyl thiotetrazole (ETT) in Acetonitrile can be used as an efficient activator reagent for the synthesis of oligonucleotides. This reagent is effective in the solid-phase synthesis of RNA oligonucleotides in terms of product yield in comparison with other reagents such as 4,5-dicyanoimidazole and 5-benzylthio-1H-tetrazole (BTT).
Analysis Note
Color (APHA): 10 max
ETT [5-(Ethylthio)-1H-tetrazole] Molarity: 0.48-0.52M
Form: Clear liquid
Water (H2O): 60ppm max
ETT [5-(Ethylthio)-1H-tetrazole] Molarity: 0.48-0.52M
Form: Clear liquid
Water (H2O): 60ppm max
Legal Information
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B
Supplementary Hazards
WGK
WGK 3
Flash Point(F)
42.1 °F
Flash Point(C)
5.6 °C
Regulatory Information
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Stefanie Hoffmann et al.
Current protocols in nucleic acid chemistry, Chapter 4, Unit 4-Unit 4 (2011-09-09)
This unit describes the solid-phase synthesis and downstream processing for RNA oligonucleotides with a length of up to 40 to 50 nucleotides on a 1- to 4-mmol scale with subsequent conjugation to PEG using the L-RNA spiegelmer NOX-E36 as an
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