AP114P
Goat Anti-Human IgM Antibody, Fc5µ, HRP conjugate
Chemicon®, from goat
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.46
eCl@ss:
32160702
Product Name
Goat Anti-Human IgM Antibody, Fc5µ, HRP conjugate, Chemicon®, from goat
biological source
goat
conjugate
peroxidase conjugate
antibody form
affinity isolated antibody
antibody product type
secondary antibodies
clone
polyclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable
western blot: suitable
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Related Categories
Application
EIA: 1:5,000-1:100,000.
Western blots: 1:5,000-1:200,000.
Immunohistochemistry: 1:500-1:5,000.
Optimal working dilutions must be determined by the end user.
Western blots: 1:5,000-1:200,000.
Immunohistochemistry: 1:500-1:5,000.
Optimal working dilutions must be determined by the end user.
Goat anti-Human IgM Antibody, Fc5μ, HRP conjugate is an antibody against Human IgM for use in ELISA & WB.
Research Category
Secondary & Control Antibodies
Secondary & Control Antibodies
Research Sub Category
Fragment Specific Secondary Antibodies
Fragment Specific Secondary Antibodies
Biochem/physiol Actions
Based on immunoelectrophoresis, the antibody reacts with the Fc5μ portion of the human IgM heavy chain. Does not react with human IgG or IgA, or with the light chains of human immunoglobulins. No reactivity against non-immunoglobulin serum proteins, but the antibody may cross-react with IgM from other species.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
IgM constitutes about 10% of serum immunoglobulins. IgM is prominent in early immune responses to most antigens and predominates in certain antibody responses such as ′natural′ blood group antibodies. IgM (with IgD) is the major immunoglobulin expressed on the surface of B cells.
Immunogen
Prepared from purified human IgM Fc5μ fragment.
Physical form
0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6 with 15mg/mL BSA. Contains no preservative. Lyophilized.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Cleopatra K Mugyenyi et al.
PloS one, 8(7), e68304-e68304 (2013-07-19)
Antibodies to P. falciparum apical membrane protein 1 (AMA1) may contribute to protective immunity against clinical malaria by inhibiting blood stage growth of P. falciparum, and AMA1 is a leading malaria vaccine candidate. Currently, there is limited knowledge of the
Sanne Reijm et al.
Arthritis research & therapy, 23(1), 230-230 (2021-09-05)
Anti-modified protein antibodies (AMPA) targeting citrullinated, acetylated and/or carbamylated self-antigens are hallmarks of rheumatoid arthritis (RA). Although AMPA-IgG cross-reactivity to multiple post-translational modifications (PTMs) is evident, it is unknown whether the first responding B cells, expressing IgM, display similar characteristics
Lin Sun et al.
Frontiers in bioengineering and biotechnology, 11, 1320586-1320586 (2023-12-21)
Plants are being increasingly recognized for the production of complex human proteins, including monoclonal antibodies (mAbs). Various methods have been applied to boost recombinant expression, with DNA codon usage being an important approach. Here, we transiently expressed three complex human
Juan Rivera-Correa et al.
eLife, 8 (2019-11-13)
Anemia is a common complication of malaria that is characterized by the loss of infected and uninfected erythrocytes. In mouse malaria models, clearance of uninfected erythrocytes is promoted by autoimmune anti-phosphatidylserine (PS) antibodies produced by T-bet+B-cells, which bind to exposed
Baoqing Sun et al.
Emerging microbes & infections, 9(1), 940-948 (2020-05-03)
The emerging COVID-19 caused by SARS-CoV-2 infection poses severe challenges to global public health. Serum antibody testing is becoming one of the critical methods for the diagnosis of COVID-19 patients. We investigated IgM and IgG responses against SARS-CoV-2 nucleocapsid (N)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
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