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biological source
human
Quality Level
antibody form
serum
manufacturer/tradename
Chemicon®
target post-translational modification
unmodified
General description
Immunoglobulin G (IgG) is the most common type of immunoglobulin present in human serum. It has the longest serum half-life compared to other immunoglobulins. IgG contains two equivalent light chains and two identical heavy chains.
Biochem/physiol Actions
Immunoglobulin G (IgG) aids in secondary immune responses. This is the only immunoglobulin type that can cross the placenta. IgG plays a major role in defense mechanisms against local and systemic infections. Polyclonal antibodies from mammalian sources has application in diagnosis.
Physical form
Format: Purified
Liquid in 0.01M PBS, filtered bt 0.45 μm.
Storage and Stability
Store at -20°C until opened. After opening dilute only enough product for a single day′s use. Store remainder at 4°C under sterile conditions for up to six months.
Other Notes
Concentration: Noted on individual vial.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 2
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Find documentation for the products that you have recently purchased in the Document Library.
CHAPTER 10 - Immunology
FABAD Journal of Pharmaceutical Sciences (2020)
Fahimeh Abdolmaleki et al.
Iranian journal of public health, 48(7), 1326-1334 (2019-09-10)
Egg yolk is a rich and accessible source of yolk immunoglobulin (Y immunoglobulin). Presently, polyclonal antibodies from mammalian sources are used for diagnosis. Antibody production from egg yolk gives a higher yield and turnover than that from lab animals, and
Respiratory infections in immunocompromised hosts
Hawaiian Entomological Society., 555-574 (2008)
Harry W Schroeder et al.
The Journal of allergy and clinical immunology, 125(2 Suppl 2), S41-S52 (2010-03-05)
Immunoglobulins are heterodimeric proteins composed of 2 heavy and 2 light chains. They can be separated functionally into variable domains that bind antigens and constant domains that specify effector functions, such as activation of complement or binding to Fc receptors.
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