ABT334
Anti-TSLP receptor Antibody
from rabbit, purified by affinity chromatography
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TSLP Receptor Antibody, TSLP Receptor, Thymic stromal lymphopoietin receptor, CRL2, ILXR, TSLPR, Cytokine receptor-like factor 2, Cytokine receptor-like 2, IL-XR
Recommended Products
biological source
rabbit
Quality Level
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
human
technique(s)
immunofluorescence: suitable
immunohistochemistry: suitable (paraffin)
western blot: suitable
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... TSLP(85480)
General description
Thymic stromal lymphopoietin (TSLP) receptor is a member of the Type I cytokine receptor family (type 5 subfamily). TSLP has been shown to play an important role in dendritic cell maturation and activation. Additionally, TSLP receptor is involved in the positive selection of regulatory T cells, induction of CD4+ T cell-mediated allergic reaction and maintenance of peripheral CD4+ T cell homeostasis. Furthermore, TSLP receptor is implicated in the development of the hematopoietic system. TSLP receptor forms a functional complex with TSLP receptor and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5. TSLP receptor is primarily expressed in dendrites and monocytes. Additionally, it is expressed in heart, skeletal muscle, kidney and adult and fetal liver; and weakly expressed in T-cells.
Immunogen
KLH-conjugated linear peptide corresponding to human TSLP receptor.
Application
Detect TLSP Receptor using this rabbit polyclonal antibody, Anti-TSLP receptor Antibody validated for use in western blotting, IHC (Paraffin) & Immunofluorescence.
Immunohistochemistry Analysis: 5 µg/mL from a representative lot detected TSLP receptor in human liver tissue.
Immunofluorescence Analysis: 20 μg/mL from a representative lot detected TSLP receptor in human liver cells.
Immunofluorescence Analysis: 20 μg/mL from a representative lot detected TSLP receptor in human liver cells.
Research Category
Signaling
Signaling
Research Sub Category
Cytokines & Cytokine Receptors
Cytokines & Cytokine Receptors
Quality
Evaluated by Western Blotting in human liver tissue lysate.
Western Blotting Analysis: 2 µg/mL of this antibody detected TSLP receptor in 15 µg of human liver tissue lysate.
Western Blotting Analysis: 2 µg/mL of this antibody detected TSLP receptor in 15 µg of human liver tissue lysate.
Target description
~53 kDa observed. Uncharacterized bands may appear in some lysate(s). Uniprot describes 2 isoforms at ~27 kDa and ~42 kDa
Physical form
Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Storage and Stability
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Control
Human liver tissue lysate
Human liver tissue lysate
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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