ABT272
Anti-SUN2 Antibody
from rabbit, purified by affinity chromatography
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All Photos(2)
Synonym(s):
SUN domain-containing protein 2, Protein unc-84 homolog B, Rab5-interacting protein, Rab5IP, Sad1/unc-84 protein-like 2
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
mouse, human
technique(s)
immunocytochemistry: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... SUN2(25777)
General description
SUN domain-containing protein 2 (SUN2), or Protein UNC-84 homolog B (UNC84B), is a single-pass nuclear envelope transmembrane protein responsible for nuclear migrations that are essential for development. SUN2 has a predicted transmembrane domain and a C-terminal region with similarity to the S. pombe spindle pole body protein Sad1. SUN2 interacts with RAB5A and is widely expressed, and highly expressed in the heart, lungs and muscles. UNC-84 may function to facilitate a nuclear-centrosomal interaction required for nuclear migration and anchorage.
Immunogen
Epitope: N-terminus
Linear peptide corresponding to the N-terminus of human Sun2.
Application
Detect SUN2 using this Anti-SUN2 antibody validated for use in western blotting & ICC.
Research Category
Cell Structure
Cell Structure
Research Sub Category
Adhesion (CAMs)
Adhesion (CAMs)
Western Blotting Analysis: A 1:500 dilution from a representative lot detected SUN2 in 10 µg of A431, Jurkat, L6, and NIH/3T3 cell lysate.
Western Blotting Analysis: A representative lot detected SUN2 recombinant protein (Haque, F., et al. (2010). Journal of Biol. Chem. 285(5): 3487-3498).
Immunocytochemistry Analysis: A representative lot detected SUN2 in human foreskin fibroblasts and NIH/3T3 cells (Haque, F., et al. (2010). Journal of Biol. Chem. 285(5): 3487-3498).
Western Blotting Analysis: A representative lot detected SUN2 recombinant protein (Haque, F., et al. (2010). Journal of Biol. Chem. 285(5): 3487-3498).
Immunocytochemistry Analysis: A representative lot detected SUN2 in human foreskin fibroblasts and NIH/3T3 cells (Haque, F., et al. (2010). Journal of Biol. Chem. 285(5): 3487-3498).
Quality
Evaluated by Western Blotting in HEK293 cell lysate.
Western Blotting Analysis: A 1:500 dilution of this antibody detected SUN2 in 10 µg of HEK293 cell lysate.
Western Blotting Analysis: A 1:500 dilution of this antibody detected SUN2 in 10 µg of HEK293 cell lysate.
Target description
~ 78 kDa observed. Uncharacterized band(s) may appear in some lysates.
Physical form
Affinity purified
Purified rabbit polyclonal in buffer containing PBS with 0.05% sodium azide.
Storage and Stability
Stable for 1 year at 2-8°C from date of receipt.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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