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Follitropin subunit beta, Follicle-stimulating hormone beta subunit, FSH-B, FSH-beta, Follitropin beta chain
Recommended Products
biological source
goat
Quality Level
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human, mouse
technique(s)
ELISA: suitable
activity assay: suitable
immunohistochemistry: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... FSHB(2488)
mouse ... Fshb(14308)
General description
FSH-beta is the critical subunit of FSH hormone, also called Follitropin, and several other hormones. The alpha subunits of LH, FSH, TSH and, hCG are identical, however the beta subunits vary determine the interaction with the receptors. The FSH-beta confers the biological specificity for several growth factors including Follitropin, Thyrotropin, Lutropin and Gonadotropin. FSH is involved in follicle and spermatogenesis and is secreted by the anterior pituitary gland. FSH is also expressed by testis, so FSH-beta can be found there as well during development and in adult tissues.
Immunogen
Linear peptide corresponding to a 13-amino acid receptor-binding sequence (LVYKDPARPNTQK) of the β-subunit of mouse FSH.
Application
Activity Assay Analysis: This antiserum was reported to neutralize FSH-induced osteoclast formation in mouse bone marrow cultures (Zhu, L.L., et al. (2012). PNAS. 109:14574-14579)
ELISA: This antiserum was reported to detect the immunogen peptide as well as full-lengh FSH by ELISA (Zhu, L.L., et al. (2012). PNAS. 109:14574-14579).
ELISA: This antiserum was reported to detect the immunogen peptide as well as full-lengh FSH by ELISA (Zhu, L.L., et al. (2012). PNAS. 109:14574-14579).
Research Category
Signaling
Signaling
Research Sub Category
Signaling Neuroscience
Signaling Neuroscience
This Anti-FSH, β-subunit Antibody is validated for use in Immunohistochemistry and Activity Assay and ELISA for the detection of FSH, β-subunit.
Quality
Evaluated by Immunohistochemistry in human testis and human fallopian tube tissue.
Immunohistochemistry Analysis: A 1:1,000 dilution of this antibody detected FSH, β-subunit in human testis and human fallopian tube tissue.
Immunohistochemistry Analysis: A 1:1,000 dilution of this antibody detected FSH, β-subunit in human testis and human fallopian tube tissue.
Target description
15 kDa (calculated); 19 kDa (glycosylated).
Physical form
Goat polyclonal serum without preservatives.
Unpurified
Storage and Stability
Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Other Notes
Concentration: Please refer to lot specific datasheet.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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