ABS463
Anti-TET3 Antibody
from rabbit, purified by affinity chromatography
Synonym(s):
Ten-eleven-translocation family 3
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
biological source
rabbit
Quality Level
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
human
technique(s)
western blot: suitable
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... TET3(200424)
General description
Methylcytosine dioxygenase TET3 (TET3) is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. TET3 is involved in the demethylation of zygotic DNA before the first mitosis and has been suggested to be involved in the epigenetic reprogramming of the zygotic paternal DNA following natural fertilization. TET3 is expressed in colon, muscle, adrenal gland, and peripheral blood lymphocytes. It is also expressed in fetal brain but not adult brain.
Immunogen
KLH-conjugated linear peptide corresponding to human TET3.
Application
Anti-TET3 Antibody is a highly specific rabbit polyclonal antibody, that targets Methylcytosine dioxygenase TET3 & has been tested in western blotting.
Research Category
Signaling
Signaling
Research Sub Category
Developmental Signaling
Developmental Signaling
Quality
Evaluated by Western Blotting/Peptide Inhibition Assay in SK-N-SH cell lysate.
Western Blotting/Peptide Inhibition Assay Analysis: 1 µg/mL of this antibody detected TET3 in 15 µg of SK-N-SH cell lysate.
Western Blotting/Peptide Inhibition Assay Analysis: 1 µg/mL of this antibody detected TET3 in 15 µg of SK-N-SH cell lysate.
Target description
~200 kDa observed. Uncharacterized bands may appear in some lysate(s). Uniprot describes 3 isoforms at ~77 kDa, ~167 kDa, and ~180 kDa
Physical form
Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Storage and Stability
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Control
SK-N-SH cell lysate
SK-N-SH cell lysate
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Cell chemical biology, 27(5), 538-550 (2020-02-27)
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