ABN476
Anti-ACVR1C Antibody
from rabbit, purified by affinity chromatography
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Activin receptor type-1C, Activin receptor type IC, ACTR-IC, Activin receptor-like kinase 7, ALK-7, ACVR1C
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biological source
rabbit
Quality Level
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
human
technique(s)
western blot: suitable
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... ACVR1C(130399)
General description
Activin receptor type-1 (ACVR1C) is a dimeric growth and differentiation factor belonging to the TKL Ser/Thr protein kinase family. Activins signal through a heteromeric complex of receptor serine kinases which include at least two, type I and two type II receptors. ACVR1C plays an important role in cell differentiation, growth arrest, and apoptosis. It is found in pancreas, heart, colon, small intestine, ovary, hippocampus, medulla oblongata, and putamen of the brain.
Immunogen
KLH-conjugated linear peptide corresponding to human ACVR1C.
Application
Detect Activin receptor type-1 using this rabbit polyclonal antibody, Anti-ACVR1C Antibody validated for use in western blotting.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Developmental Neuroscience
Developmental Neuroscience
Quality
Evaluated by Western Blotting in human placenta tissue lysate.
Western Blotting Analysis: 1 µg/mL of this antibody detected ACVR1C in 15 µg of human placenta tissue lysate.
Western Blotting Analysis: 1 µg/mL of this antibody detected ACVR1C in 15 µg of human placenta tissue lysate.
Target description
~62 kDa observed. Uniprot describes 4 isoforms at ~37 kDa, ~46 kDa, ~50 kDa, and ~55 kDa Uncharacterized bands may appear in some lysates.
Physical form
Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Storage and Stability
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Control
Human placenta tissue lysate
Human placenta tissue lysate
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
recommended
Product No.
Description
Pricing
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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