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ABC512

Sigma-Aldrich

Anti-ST6GAL1 Antibody

from rabbit, purified by affinity chromatography

Synonym(s):

Beta-galactoside alpha-2,6-sialyltransferase 1, Alpha 2,6-ST 1, B-cell antigen CD75, CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1, ST6Gal I, ST6GalI, Sialyltransferase 1

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

species reactivity (predicted by homology)

chimpanzee (based on 100% sequence homology), primate (based on 100% sequence homology)

technique(s)

immunohistochemistry: suitable
western blot: suitable

NCBI accession no.

NP_003023

UniProt accession no.

P15907

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... ST6GAL1(6480)

General description

ST6GAL1, also known as Beta-galactoside alpha-2/ 6-sialyltransferase 1, or Alpha 2/ 6-ST 1, and encoded by the gene symbol ST6GAL1/ SIAT1, is a member of the glycosyltransferase 29 family. ST6GAL1 has been implied to play an important role in the transfer of sialic acid from the donor of substrate CMP-sialic acid to galactose containing acceptor substrates. The membrane-bound form of ST6GAL1 is located in trans-cisternae of Golgi apparatus. The soluble form of ST6GAL1 is derived from the membrane form by proteolytic processing. ST6GAL1 is located in the Golgi apparatus, Golgi stack membrane, and the Single-pass type II membrane protein.

Immunogen

Epitope: Lumenal domain
KLH-conjugated linear peptide corresponding to the Lumenal domain of human ST6GAL1.

Application

Anti-ST6GAL1 is an antibody against ST6GAL1 for use in WB, IH.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected ST6GAL1 in human prostate and human liver cancer tissue.
Research Category
Apoptosis & Cancer
Research Sub Category
Apoptosis - Additional

Quality

Evaluated by Western Blotting in human skeletal muscle tissue lysate.

Western Blotting Analysis: 2.0 µg/mL of this antibody detected ST6GAL1 in 10 µg of human skeletal muscle tissue lysate.

Target description

~41 kDa observed. The calculated molecular weight is 47 kDa, however ST6GAL1 has been shown as a ~41 kDa band in western blots (Minyoung, L., et al. (2008). Mol. Cancer Research. 6:1316-1325).

Physical form

Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Other Notes

Concentration: Please refer to lot specific datasheet.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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