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ABC139

Sigma-Aldrich

Anti-TSPO Antibody

from rabbit, purified by affinity chromatography

Synonym(s):

Translocator protein, Mitochondrial benzodiazepine receptor, PKBS, Peripheral-type benzodiazepine receptor, PBR

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

technique(s)

immunohistochemistry: suitable
western blot: suitable

NCBI accession no.

NP_000705.2

UniProt accession no.

P30536

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... TSPO(706)

General description

Translocator protein (TSPO) is also called Mitochondrial benzodiazepine receptor, PKBS, or Peripheral-type benzodiazepine receptor (PBR). TSPO generates peripheral-type benzodiazepine recognition sites. TSPO has a role in cholesterol transport across mitochondrial membranes in steroidogenic cells, and may also be involved in in the transport of porphyrins and heme. TSPO is found in many tissue types, but is normally found expressed at the highest levels in steroid synthesizing tissues.

Specificity

This antibody recognizes the C-terminus of TSPO.

Immunogen

Epitope: C-terminus
KLH-conjugated linear peptide corresponding to the C-terminus of human TSPO.

Application

Anti-TSPO Antibody is a rabbit polyclonal antibody, validated for use in western blotting & IHC.
Research Category
Apoptosis & Cancer
Research Sub Category
Apoptosis - Additional
Western Blotting Analysis: 1.0 µg/mL from a representative lot detected TSPO in 10 µg of HeLa cell lysate.
Immunohistochemistry Analysis: A 1:500-2,000 dilution from a representative lot detected TSPO in human thalamus, human cardiac myocytes and human cerebellum tissue.

Quality

Evaluated by Western Blotting in human testis tissue lysate.

Western Blotting Analysis: 0.25 µg/mL of this antibody detected TSPO in 10 µg of human testis tissue lysate.

Target description

~16 kDa observed

Linkage

Replaces: MABC650

Physical form

Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
Human testis tissue lysate

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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