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AB9702

Sigma-Aldrich

Anti-Tyrosine Hydroxylase Antibody

Chemicon®, from chicken

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Synonym(s):
TH
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

chicken

Quality Level

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human, mouse

manufacturer/tradename

Chemicon®

technique(s)

immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

isotype

IgY

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... TH(7054)

Specificity

Recognizes Tyrosine Hydroxylase

Immunogen

Synthetic peptides from human/mouse Tyrosine Hydroxylase

Application

Anti-Tyrosine Hydroxylase Antibody is an antibody against Tyrosine Hydroxylase for use in IC, IH & WB.
Immunohistochemistry: 1:1000-1:2000 using 2% paraformaldehyde fixed tissues.
Immunocytochemistry: 1:1000-1:2000 using 2% paraformaldehyde fixed cells.
Western Blotting: 1:2000-1:5000

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors

Neuronal & Glial Markers

Physical form

Affinity purified chicken IgY. Two different antibodies were combined to make this product. Liquid in PBS, pH 7.2 with 0.02% sodium azide.

Storage and Stability

Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Antonella Meloni et al.
The Journal of clinical endocrinology and metabolism, 104(1), 150-162 (2018-10-20)
In autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED), autoantibodies (AutoAbs) labeling brain neurons were reported; conversely, brain MRI alterations associated with these AutoAbs were never reported. To describe brain alterations in APECED and to correlate them with AutoAbs against glutamic acid decarboxylase (GAD)
Florian Groessl et al.
Nature neuroscience, 21(7), 952-962 (2018-06-29)
Functional neuroanatomy of Pavlovian fear has identified neuronal circuits and synapses associating conditioned stimuli with aversive events. Hebbian plasticity within these networks requires additional reinforcement to store particularly salient experiences into long-term memory. Here we have identified a circuit that
Laura Angioni et al.
Hormones and behavior, 83, 23-38 (2016-05-18)
Oxytocin is involved in the control of different behaviors, from sexual behavior and food consumption to empathy, social and affective behaviors. An imbalance of central oxytocinergic neurotransmission has been also associated with different mental pathologies, from depression, anxiety and anorexia/bulimia
Ryan M Grippo et al.
Current biology : CB, 27(16), 2465-2475 (2017-08-07)
Dopamine (DA) neurotransmission controls behaviors important for survival, including voluntary movement, reward processing, and detection of salient events, such as food or mate availability. Dopaminergic tone also influences circadian physiology and behavior. Although the evolutionary significance of this input is
Thomas Andreska et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 40(33), 6289-6308 (2020-07-12)
Motor learning depends on synaptic plasticity between corticostriatal projections and striatal medium spiny neurons. Retrograde tracing from the dorsolateral striatum reveals that both layer II/III and V neurons in the motor cortex express BDNF as a potential regulator of plasticity

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