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AB5449

Sigma-Aldrich

Anti-Tropomyosin 4 Antibody

serum, Chemicon®

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Synonym(s):
Tm4
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human, mouse, rat

manufacturer/tradename

Chemicon®

technique(s)

immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... TPM4(7171)

Specificity

Recognizes Tropomyosin 4.

Immunogen

Synthetic peptide corresponding to the 9d exon from the delta gene of tropomyosin.

Application

Detect Tropomyosin 4 using this Anti-Tropomyosin 4 Antibody validated for use in WB, IC, IH.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Irina Pleines et al.
The Journal of clinical investigation, 127(3), 814-829 (2017-01-31)
Platelets are anuclear cells that are essential for blood clotting. They are produced by large polyploid precursor cells called megakaryocytes. Previous genome-wide association studies in nearly 70,000 individuals indicated that single nucleotide variants (SNVs) in the gene encoding the actin
J N Martin et al.
Neuroscience, 164(2), 563-572 (2009-08-12)
DYT1, the most common inherited dystonia, is caused by a common dominant mutation in the TOR1A gene that leads to a glutamic acid deletion in the protein torsinA. Wild-type torsinA locates preferentially in the endoplasmic reticulum while the disease-linked mutant
Andrius Masedunskas et al.
Journal of cell science, 131(6) (2018-03-01)
Many actin filaments in animal cells are co-polymers of actin and tropomyosin. In many cases, non-muscle myosin II associates with these co-polymers to establish a contractile network. However, the temporal relationship of these three proteins in the de novo assembly
Sharissa L Latham et al.
Nature communications, 9(1), 4250-4250 (2018-10-14)
Germline mutations in the ubiquitously expressed ACTB, which encodes β-cytoplasmic actin (CYA), are almost exclusively associated with Baraitser-Winter Cerebrofrontofacial syndrome (BWCFF). Here, we report six patients with previously undescribed heterozygous variants clustered in the 3'-coding region of ACTB. Patients present
Kimiyasu Shiraki et al.
Journal of medical virology, 96(1), e29379-e29379 (2024-01-18)
Although neonates are commonly exposed to vaginal herpes simplex virus (HSV)-2, neonatal herpes is rare. Therefore, we analyzed paired infant and maternal HSV-2 isolates from two cases of mother-to-infant transmission to identify viral factors contributing to vertical transmission. Sixteen infant

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