AB3610
Anti-Survivin Antibody
serum, Chemicon®
Synonym(s):
TIAP
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
biological source
rabbit
Quality Level
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... BIRC5(332)
General description
Apoptosis is triggered by a variety of stimuli, including members of the Tumor Necrosis Factor (TNF) family, and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases. One of these IAP proteins, Survivin/TIAP, interacts with the processed form of caspase-3 and has been shown to inhibit its proteolytic activity. Survivin/TIAP is predominantly expressed in tissues of embryos, transformed cell lines, and many human cancers and lymphomas.
Immunogen
Recombinant, GST-tagged full length human Survivin
Application
Immunoblotting: Recommended antibody dilution 1:3000-6000
Immunoprecipitation: Recommended antibody dilution 1:200
Immunohistochemisty: Recommended antibody dilution 1:1500
Optimal antibody dilutions must be determined by end-user.
Immunoprecipitation: Recommended antibody dilution 1:200
Immunohistochemisty: Recommended antibody dilution 1:1500
Optimal antibody dilutions must be determined by end-user.
This Anti-Survivin Antibody is validated for use in WB, IP, IH for the detection of Survivin.
Physical form
Serum with no preservatives
Storage and Stability
Maintain at -20°C for up to 6 months after date of receipt.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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Product No.
Description
Pricing
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Inhibition of IL-6 expression in LNCaP prostate cancer cells by a combination of atorvastatin and celecoxib.
Wang, H; Cui, XX; Goodin, S; Ding, N; Van Doren, J; Du, Z; Huang, MT; Liu, Y; Cheng et al.
Oncology Reports null
Oral Free Paper Sessions.
Virchows Archiv : an international journal of pathology, 469 Suppl 1, 1-346 (2016-08-25)
Linfei Hu et al.
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