AB2960
Anti-UVRAG Antibody
from rabbit, purified by affinity chromatography
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All Photos(3)
Synonym(s):
UV radiation resistance-associated gene protein, p63
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
rabbit
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
mouse, human, rat
technique(s)
immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... UVRAG(7405)
General description
UV irradiation resistance-associated gene (UVRAG) is an essential component of the Beclin1-PI(3)KC3 lipid kinase complex which functions as an important signaling checkpoint for autophagy and tumor-cell growth. More specifically, UVRAG seems to work as a multivalent trafficking effector that controls autophagosome formation and maturation, and also controls the engaging of the fusion apparatus to the endosome. UVRAG may be a promising target for cancer therapies.
Specificity
This antibody recognizes the C-terminus of UVRAG.
Immunogen
Epitope: C-terminus
KLH-conjugated linear peptide corresponding to the C-terminus of human UVRAG.
Application
Anti-UVRAG Antibody is an antibody against UVRAG for use in WB, IC & IP.
Immunoprecipitation Analysis: 10 µg from a representative lot immunoprecipitated UVRAG from 500 µg from Raji cell lysate.
Immunocytochemistry Analysis: A 1:500 dilution from a representative lot detected UVRAG in NIH/3T3 and A431 cells.
Immunocytochemistry Analysis: A 1:500 dilution from a representative lot detected UVRAG in NIH/3T3 and A431 cells.
Research Category
Apoptosis & Cancer
Apoptosis & Cancer
Research Sub Category
Apoptosis - Additional
Apoptosis - Additional
Quality
Evaluated by Western Blot in Raji cell lysate.
Western Blot Analysis: 0.1 µg/mL of this antibody detected UVRAG in 10 µg of Raji cell lysate.
Western Blot Analysis: 0.1 µg/mL of this antibody detected UVRAG in 10 µg of Raji cell lysate.
Target description
~78 kDa observed
Physical form
Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Storage and Stability
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Control
Raji cell lysate
Raji cell lysate
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Articles
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